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Bacterial Meningitis in Older Neonates

Eric T. Baumgartner, MD; R. Ann Augustine, RN, PNP; Russell W. Steele, MD
Am J Dis Child. 1983;137(11):1052-1054. doi:10.1001/archpedi.1983.02140370014005.
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• During a five-year period, 24 patients' conditions (age range, 2 to 6 weeks) were diagnosed, and they were treated for bacterial meningitis. Organisms recovered from the CSF included group B Streptococcus (n = 6), Escherichia coli (n = 5), Listeria monocytogenes (n = 5), Hemophilus influenzae (n = 4), Streptococcus pneumoniae (n = 2), and group D and group A Streptococcus (one each). Initial antimicrobial therapy must include antibiotics that are effective across this spectrum of potential pathogens. Symptoms and signs were often subtle. Six children (25%) experienced major neurologic residua, including five patients (21%) in whom hydrocephalus developed. Ultrasound examination of the head at the end of therapy was an effective technique for early assessment of neurologic sequelae.

(Am J Dis Child 1983;137:1052-1054)

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