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Dietary Intake of Lead and Blood Lead Concentration in Early Infancy

Jacqueline E. Ryu, MS, RD; Ekhard E. Ziegler, MD; Steven E. Nelson; Samuel J. Fomon, MD
Am J Dis Child. 1983;137(9):886-891. doi:10.1001/archpedi.1983.02140350060015.
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• Under circumstances of low prenatal exposure to lead and low nondietary exposure to lead postnatally, four breast-fed infants and 25 formula-fed infants were studied to determine the relation between dietary intake of lead and blood lead concentration. From 8 through 111 days of age, the mean dietary intake of lead by the formula-fed infants was 17 μg/day (3 to 4 μg/kg/day), and intake of lead by the breast-fed infants was estimated to be only slightly greater. The mean blood lead concentration at the age of 112 days was 6.1 μg/dL. From 112 through 195 days of age, 17 infants continued in the study: ten received a mean dietary intake of lead of 16 μg/day, and seven received a mean intake of 61 μg/day. At 196 days of age, mean blood lead concentrations were significantly different (7.2 and 14.4 μg/dL, respectively).

(Am J Dis Child 1983;137:886-891)

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