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Acquired Immunodeficiency Syndrome in Infants

ARYE RUBINSTEIN, MD
Am J Dis Child. 1983;137(9):825-827. doi:10.1001/archpedi.1983.02140350003001.
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Acquired immunodeficiency syndrome (AIDS) was first believed to be confined to male homosexuals.1-4 Subsequently, the same syndrome has been seen among intravenous (IV) drug users,5 Haitians,6 hemophiliacs7,8 and other recipients of blood products, and, more recently, in female sexual partners of patients with AIDS.9 This ever broadening spectrum of AIDS victims has raised the possibility of a causative transmissible agent(s). The discovery of a condition similar to AIDS in infants and their mothers10,11 is probably the most important step in elucidating the dissemination of the disease to the heterosexual population.

Early in 1982, my colleagues and I described what we believed to be the first five infants with an AIDS-like disease.10 Since then, the number of cases rose to seven by July 1982,11 13 by January 1983,12 and 26 by July 1983. We identified these children in the Bronx, a borough of

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