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May 1983, Vol 137, No. 5 >
Article | May 1983

Benzyl Alcohol Poisoning FREE

WILLIAM R. JARVIS, MD; JAMES M. HUGHES, MD; JANET L. MOSSER, RRA; JAMES R. ALLEN, MD; ROBERT W. HALEY, MD
Am J Dis Child. 1983;137(5):505. doi:10.1001/archpedi.1983.02140310083026.
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Sir.—In the marginal comment "Fatal Benzyl Alcohol Poisoning in Neonatal Intensive Care Units: A New Concern for Pediatricians" (Journal 1982; 136: 974-975), Lovejoy described the newly reported gasping syndrome associated with the use of benzyl alcohol-preserved solutions. On the basis of these data, the Food and Drug Administration sent letters to health care personnel urging them not to use benzyl alcohol-preserved solutions in premature infants.1-4 At approximately the same time, a summary of the available data concerning the syndrome and the FDA warning was published in the Centers for Disease Control's Morbidity and Mortality Weekly Report.5

Because all premature infants delivered in the United States would be at theoretical risk for exposure to benzyl alcohol-preserved solutions, these warnings were of considerable public health significance. To evaluate the effect of the FDA warning, we did a mail survey in September 1982 of past and present benzyl alcohol preservative use

REFERENCES

1 +
Gershanik JJ, Boecler G, George W, et al:  The gasping syndrome: Benzyl alcohol (BA) poisoning? Clin Res 1981;;29:895.
2 +
Brown WI, Buist NRM, Gipson HT, et al:  Fatal benzyl alcohol poisoning in a neonatal intensive care unit . Lancet 1982;;1:1250-1251.
3 +
Gershanik JJ, Boecler G, Ensley H, et al:  The gasping syndrome and benzyl alcohol poisoning . N Engl J Med 1982;;307:1384-1388.
4 +
Food and Drug Administration Bulletin , Dept of Health and Human Services, (May 28) , 1982;.
5 +
 Neonatal deaths associated with use of benzyl alcohol—United States . MMWR 1982;;31: 290-291.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Gershanik JJ, Boecler G, George W, et al:  The gasping syndrome: Benzyl alcohol (BA) poisoning? Clin Res 1981;;29:895.
2 +
Brown WI, Buist NRM, Gipson HT, et al:  Fatal benzyl alcohol poisoning in a neonatal intensive care unit . Lancet 1982;;1:1250-1251.
3 +
Gershanik JJ, Boecler G, Ensley H, et al:  The gasping syndrome and benzyl alcohol poisoning . N Engl J Med 1982;;307:1384-1388.
4 +
Food and Drug Administration Bulletin , Dept of Health and Human Services, (May 28) , 1982;.
5 +
 Neonatal deaths associated with use of benzyl alcohol—United States . MMWR 1982;;31: 290-291.

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