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Article |

A Model for Studying the Pathogenesis and Incidence of Low-Birth-Weight Infants

Herbert C. Miller, MD
Am J Dis Child. 1983;137(4):323-327. doi:10.1001/archpedi.1983.02140300005002.
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• A model is proposed for analyzing the many extrinsic and intrinsic factors that might affect the incidence of low-birth-weight (LBW) infants (<2,501 g) adversely in populations of variable socioeconomic status (SES). The model provides for categorizing all mothers either into one of four broad categories of extrinsic factors or into a normal group, free of all extrinsic factors. Application of the model in a prospective study of 972 infants showed that the incidence of LBW infants was low in normal pregnancies and significantly higher in the categories of extrinsic factors, that SES had a limited role in the birth of LBW infants, and that intrinsic factors had an almost negligible adverse effect if properly controlled.

(Am J Dis Child 1983;137:323-327)


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