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September 1982, Vol 136, No. 9 >
Article | September 1982

Spectrum of Amebiasis in Children FREE

Russell J. Merritt, MD, PhD; Edward Coughlin, MD; Daniel W Thomas, MD; Leena Jariwala, MD; Virginia Swanson, MD; Frank R. Sinatra, MD
[+] Author Affiliations

Reprint requests to Department of Pediatrics, Children's Hospital of Los Angeles, 4650 Sunset Blvd, Los Angeles, CA 90027 (Dr Merritt).


Am J Dis Child. 1982;136(9):785-789. doi:10.1001/archpedi.1982.03970450027007.
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• In 11 patients with childhood amebiasis, only two had dysentery. Additional clinical findings included hematochezia without diarrhea (four patients), dysentery with appendicitis (one patient), exacerbation of ulcerative colitis (two patients), and disseminated infantile amebiasis (two patients). All patients with hematochezia examined by proctosigmoidoscopy had colitis. The diagnosis of amebiasis was confirmed by microscopic examination of fresh stool specimens, pathologic findings, and/or serologic titers. Amebiasis should be considered in the differential diagnosis of infants and children with hematochezia or hepatomegaly, especially in endemic areas.

(Am J Dis Child 1982;136:785-789)

REFERENCES

1 +
Mahmoud AAF, Warren KS:  Algorithms in the diagnosis and management of exotic diseases: XVII. Amebiasis . J Infect Dis 1976;;134:639-643.
2 +
Harrison HR, Crowe CP, Fulginiti VA:  Amoebic liver abscess in children: Clinical and epidemiologic features . Pediatrics 1979;;64:923-928.
3 +
Dykes AC, Ruebush TK III, Gorelkin L, et al:  Extraintestinal amebiasis in infancy: Report of three patients and epidemiological investigations of their families . Pediatrics 1980;;65:799-803.
4 +
Healy GR:  Laboratory diagnosis of amebiasis . Bull NY Acad Med 1971;;47:478-493.
5 +
Healy GR, Cahill KM:  The serology of amebiasis . Bull NY Acad Med 1971;;47:494-507.
6 +
Scully RE, Galdabini JJ, McNeely BV:  Case 32-1977, Case records of the Massachusetts General Hospital: Weekly clinicopathological exercises . N Engl J Med 1977;;297:322-330.
7 +
Dehner LP, Kissane JM:  Pyogenic liver abscesses in infancy and childhood . J Pediatr 1969;;74:763-773.
8 +
Kanani SR, Knight R:  Relapsing amoebic colitis of 12 years exacerbated by corticosteroids . Br Med J 1969;;2:613-614.
9 +
 Misdiagnosis of amebiasis , editorial. Br Med J 1978;;3:379.
10 +
Krogstad DJ, Spencer HC, Healy GR, et al:  Amebiasis: Epidemiologic studies in the United States, 1971-74 . Ann Intern Med 1978;;88;89-97.
11 +
Serafín-Anaya FJ, Castañeda-Castañeira E, Diaz S, et al:  Amebiasis intestinal en niños: II. Evalación de diversas técnicas diagnósticas y distinctos esquemas terapéuticos . Arch Invest Med 1978;;9( (suppl 1) ):371-374.
12 +
Krupp IM:  Comparison of counter immunoelectrophoresis with other serological tests in the diagnosis of amebiasis . Am J Trop Med Hyg 1974;;23:27-30.
13 +
Patterson M, Healy GR, Sitabot JM:  Serological testing for amebiasis . Gastroenterology 1980;;78:136-141.
14 +
Yang J, Kennedy MT:  Evaluation of enzyme-linked immunosorbent assay for the serodiagnosis of amebiasis . J Clin Microbiol 1979;;10:778-785.
15 +
Rollo IM:  Drugs used in the chemotherapy of amebiasis , in Goodman LS, Gilman A (eds): The Pharmacologic Basis of Therapeutics , ed 4. New York, Macmillan Publishing Co Inc, 1970;, pp 1129-1130.
16 +
Weinstein L:  Antibiotics: III. The tetracyclines , in Goodman LS, Gilman A (eds): The Pharmacologic Basis of Therapeutics , ed 4. New York, Macmillan Publishing Co Inc, 1979;, p 1260.
17 +
Fleisher DI, Hepler RS, Landau JW:  Blindness during diiodohydroxyquin (Diodoquin) therapy: A case report . Pediatrics 1974;;54:106-108.
18 +
Kanani SR, Knight R:  Experiences with the use of metronidazole in the treatment of nondysenteric intestinal amebiasis . Trans R Soc Trop Med Hyg 1972;;66:244-249.
19 +
Beard CM, Noller KC, O'Fallon WM, et al:  Lack of evidence for cancer due to use of metronidazole . N Engl J Med 1979;;301:519-522.
20 +
Spencer HC, Muchnick C, Sexton DJ:  Endemic amebiasis in an extended family . Am J Trop Med Hyg 1977;;26:628-635.
21 +
Wolfe MS:  Nondysenteric intestinal amebiasis: Treatment with diloxanide furoate . JAMA 1973;;224:1601-1604.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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References

1 +
Mahmoud AAF, Warren KS:  Algorithms in the diagnosis and management of exotic diseases: XVII. Amebiasis . J Infect Dis 1976;;134:639-643.
2 +
Harrison HR, Crowe CP, Fulginiti VA:  Amoebic liver abscess in children: Clinical and epidemiologic features . Pediatrics 1979;;64:923-928.
3 +
Dykes AC, Ruebush TK III, Gorelkin L, et al:  Extraintestinal amebiasis in infancy: Report of three patients and epidemiological investigations of their families . Pediatrics 1980;;65:799-803.
4 +
Healy GR:  Laboratory diagnosis of amebiasis . Bull NY Acad Med 1971;;47:478-493.
5 +
Healy GR, Cahill KM:  The serology of amebiasis . Bull NY Acad Med 1971;;47:494-507.
6 +
Scully RE, Galdabini JJ, McNeely BV:  Case 32-1977, Case records of the Massachusetts General Hospital: Weekly clinicopathological exercises . N Engl J Med 1977;;297:322-330.
7 +
Dehner LP, Kissane JM:  Pyogenic liver abscesses in infancy and childhood . J Pediatr 1969;;74:763-773.
8 +
Kanani SR, Knight R:  Relapsing amoebic colitis of 12 years exacerbated by corticosteroids . Br Med J 1969;;2:613-614.
9 +
 Misdiagnosis of amebiasis , editorial. Br Med J 1978;;3:379.
10 +
Krogstad DJ, Spencer HC, Healy GR, et al:  Amebiasis: Epidemiologic studies in the United States, 1971-74 . Ann Intern Med 1978;;88;89-97.
11 +
Serafín-Anaya FJ, Castañeda-Castañeira E, Diaz S, et al:  Amebiasis intestinal en niños: II. Evalación de diversas técnicas diagnósticas y distinctos esquemas terapéuticos . Arch Invest Med 1978;;9( (suppl 1) ):371-374.
12 +
Krupp IM:  Comparison of counter immunoelectrophoresis with other serological tests in the diagnosis of amebiasis . Am J Trop Med Hyg 1974;;23:27-30.
13 +
Patterson M, Healy GR, Sitabot JM:  Serological testing for amebiasis . Gastroenterology 1980;;78:136-141.
14 +
Yang J, Kennedy MT:  Evaluation of enzyme-linked immunosorbent assay for the serodiagnosis of amebiasis . J Clin Microbiol 1979;;10:778-785.
15 +
Rollo IM:  Drugs used in the chemotherapy of amebiasis , in Goodman LS, Gilman A (eds): The Pharmacologic Basis of Therapeutics , ed 4. New York, Macmillan Publishing Co Inc, 1970;, pp 1129-1130.
16 +
Weinstein L:  Antibiotics: III. The tetracyclines , in Goodman LS, Gilman A (eds): The Pharmacologic Basis of Therapeutics , ed 4. New York, Macmillan Publishing Co Inc, 1979;, p 1260.
17 +
Fleisher DI, Hepler RS, Landau JW:  Blindness during diiodohydroxyquin (Diodoquin) therapy: A case report . Pediatrics 1974;;54:106-108.
18 +
Kanani SR, Knight R:  Experiences with the use of metronidazole in the treatment of nondysenteric intestinal amebiasis . Trans R Soc Trop Med Hyg 1972;;66:244-249.
19 +
Beard CM, Noller KC, O'Fallon WM, et al:  Lack of evidence for cancer due to use of metronidazole . N Engl J Med 1979;;301:519-522.
20 +
Spencer HC, Muchnick C, Sexton DJ:  Endemic amebiasis in an extended family . Am J Trop Med Hyg 1977;;26:628-635.
21 +
Wolfe MS:  Nondysenteric intestinal amebiasis: Treatment with diloxanide furoate . JAMA 1973;;224:1601-1604.

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