July 1982, Vol 136, No. 7 >

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Article | July 1982

Use of Urinary Indexes in Renal Failure in the Newborn

Eileen N. Ellis, MD; Watson C. Arnold, MD

Am J Dis Child. 1982;136(7):615-617. doi:10.1001/archpedi.1982.03970430047013.

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• Causes of renal failure and urinary indexes were recorded in 45 neonates with oliguria and uremia. Twenty (44%) had ischemic renal damage; nine of these infants recovered and 11 died. Eight infants (18%) had various other causes of renal insufficiency. Determination of serum BUN or creatinine concentrations did not differentiate between these groups. Fractional excretion of sodium (FE_Na) and renal failure index (RFI) determined on serum and first-voided urine samples were statistically different between the neonates with prerenal uremia and the neonates with ischemic renal damage, although there was overlap between the groups. A neonate with an FE_Na less than 2.5% and an RFI less than 2.5 is said to have prerenal uremia. An FE_Na greater than 2.5% or an RFI greater than 2.5 in a neonate suggests ischemic renal disease; however, some neonates with prerenal uremia may have values in this range.

(Am J Dis Child 1982;136:615-617)

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Ellis EN, Arnold WC. Use of Urinary Indexes in Renal Failure in the Newborn. Am J Dis Child. 1982;136(7):615-617. doi:10.1001/archpedi.1982.03970430047013.

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