0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Second Malignancy in Acute Lymphocytic Leukemia

SUSUMU INOUE, MD; YADDANAPUDI RAVINDRANATH, MBBS; JEANNE M. LUSHER, MD
Am J Dis Child. 1982;136(2):175-176. doi:10.1001/archpedi.1982.03970380087024.
Text Size: A A A
Published online

Sir.—We read with interest the article "Second Malignancy in Acute Lymphocytic Leukemia: Review of 33 Cases" by Drs Mosijczuk and Ruymann in the Journal (1981;135:313-316). In the article the authors state, referring to four patients in whom chronic myelogenous leukemia (CML) developed after treatment of acute lymphocytic leukemia (ALL), that no patients had cytogenetic studies performed at the time of the initial diagnosis of ALL. We wish to point out that in a previous study,1 quoted by Drs Mosijczuk and Ruymann, we did describe the cytogenetic data at the time of the occurrence of ALL in one of the patients (patient 4) the authors referred to. The karyotype of that initial marrow, as well as six subsequent consecutive remission marrows, were normal. The cytogenetic aspect on this patient was also separately published together with chromosome data from another two patients with juvenile CML.2 Unlike adult-type CML with

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();