Kawasaki's disease, an acute febrile illness of unknown cause, is being recognized more frequently in the United States.1-3 There have been reports of Kawasaki's disease associated with hydrops of gallbladder,4 aseptic meningitis, cholestasis, cardiovascular disease, and one case of myositis.5 I studied a second case of myositis associated with Kawasaki's disease, which suggests a causal relationship.
Report of a Case.—An 18-month-old girl, who had been in good health, was admitted to a hospital because of a high fever. Over the next 24 hours, the fever worsened and did not respond to administration of antipyretics and oral antibiotics (ampicillin sodium). The physical examination at that time revealed an irritable child with bilateral conjunctivitis, dryness, redness and fissuring of the lips, strawberry-like tongue, diffuse reddening of the oral and pharyngeal mucosa, and cervical lymphadenopathy.
On the fifth day of her hospitalization, a polymorphic nonvesicular truncal rash developed,