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Extrahepatic Biliary Atresia and Renal Anomalies in Fetal Alcohol Syndrome

THOMAS H. DUNIGAN, MD; STEVEN L. WERLIN, MD
Am J Dis Child. 1981;135(11):1067-1068. doi:10.1001/archpedi.1981.02130350067022.
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Since the fetal alcohol syndrome (FAS) was first described in 1973,1 a variety of associated anomalies have been reported. We discuss a case of FAS with associated extrahepatic biliary atresia and renal anomalies.

Report of a Case.—A 1,450-g girl was born to a 35-year-old mother after a 35-week gestation. The pregnancy was complicated by heavy alcohol ingestion, ranging from six to 12 drinks per day. A previous pregnancy six years earlier had resulted in a normal delivery and healthy older sibling. The diagnosis of FAS was made on the basis of the history and classic clinical features.

At 24 hours of age, the patient was noted to be jaundiced, and phototherapy was begun. Laboratory evaluation in the neonatal period included a negative Coombs' test and negative hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (HBsAb) tests. At 11 weeks of age, she was transferred to Milwaukee

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