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Systemic Amyloidosis in Cystic Fibrosis

JAIME VILASECA, MD; JAVIER CUEVAS, MD; MANUEL FRESNO, MD; JORGE TOR, MD; JAIME GUARDIA, MD; RICARDO BACARDI, MD
Am J Dis Child. 1981;135(7):667. doi:10.1001/archpedi.1981.02130310071025.
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Secondary amyloidosis has been described in association with a large number of chronic diseases. Although viscidosis is associated with chronic suppuration, the presence of amyloidosis as a complication has been reported in only three cases.1.2 Here we present a new case, to our knowledge the third in the English literature.

Report of a Case.—A male patient received a diagnosis of cystic fibrosis based on repeated respiratory infections, steatorrhea, and a positive sweat test result (chloride content, 110 mEq/L) at 6 years of age. Two siblings died of bronchopulmonary processes when they were a few weeks old.

He suffered from frequent and prolonged respiratory infections. The chest roentgenogram gave evidence of the existence of bronchiectasis. When he was 11 years of age, an increase in the thyroid size was noticed, and this led to treatment with strong iodine solution. The thyroid size continued to increase gradually. When the patient

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