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Epidural Metastasis by Wilms' Tumor FREE

Christopher T. Bever, MD; M. Richard Koenigsberger, MD; John L. Antunes, MD; James A. Wolff, MD
Am J Dis Child. 1981;135(7):644-646. doi:10.1001/archpedi.1981.02130310048016.
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• Metastatic spread is common in Wilms' tumor, but spinal epidural involvement is rare. We studied two patients in whom spinal cord compression developed during treatment for Wilms' tumor. Both patients had back pain and new pulmonary metastases months after the primary diagnosis was established. One case had evidence of adjacent vertebral involvement, and successful therapy was begun while the patient had minimal neurological deficits. The second patient had back pain initially without neurological deficit or abnormality on plain spine films, followed in one month by a rapid neurological deterioration. Despite a slow and nearly complete recovery after treatment with laminectomy, radiotherapy, and chemotherapy, her condition relapsed one year later, with a compressive lesion at a higher level. Our experience stresses the importance of early recognition and treatment of this complication of Wilms' tumor.

(Am J Dis Child 1981;135:644-646)

REFERENCES

Traggis DG, Filler RM, Druckman H, et al:  Prognosis in neuroblastoma with paralysis . J Pediatr Surg 1977;;12:419-425.
Ledlie EM, Mynors LS, Draper GJ, et al:  The natural history and treatment of Wilms' tumor . Br Med J 1970;;4:195-200.
Bannayan GA, Guvos AG, D'Angio GJ:  Effect of irradiation on the maturation of Wilms' tumor . Cancer 1971;;27:812-818.
Lemerle EM, Tournade M, Gerard-Marchant R, et al:  Wilms' tumor: Natural history and prognostic factors . Cancer 1976;;37:2557-2566.
Silva-Sosa M, Gonzaltez-Carna JL:  Wilms' tumor in children . Prog Clin Cancer 1966;;2:323-334.
Melville RL:  Pitfalls of early diagnosis of spinal cord compression in children . S Afr Med J 1975;;50:621-624.
D'Angio GJ, Beckwith JB, Breslow N, et al:  The results of the Second National Wilms' Tumor Study . Proc Am Soc Clin Oncol 1979;;20:309.
D'Angio GJ, Evans AE, Breslow N, et al:  The treatment of Wilms' tumor: Results of the National Wilms' Tumor Study . Cancer 1976;; 38:633-640.
Gilbert RW, Kim J, Posner JB:  Epidural spinal cord compression from metastatic tumor . Ann Neurol 1978;;3:40-49.
Anderson FM, Carson MJ:  Spinal cord tumors in children . J Pediatr 1953;;43:190-207.
Matson DD, Tachdjian MO:  Intraspinal tumors in infants and children: Review of 115 cases . Postgrad Med 1963;;34:279-295.
Auld A, Buerman A:  Metastatic spinal epidural tumors . Arch Neurol 1966;;15:100-105.
Barron KD, Hirano A, Araki S, et al:  Experiences with metastatic neoplasms involving the spinal cord . Neurology 1959;;9:91-103.
Sellwood RB:  The radiological approach to metastatic cancer of the brain and spine . Br J Radiol 1972;;45:647-653.

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References

Traggis DG, Filler RM, Druckman H, et al:  Prognosis in neuroblastoma with paralysis . J Pediatr Surg 1977;;12:419-425.
Ledlie EM, Mynors LS, Draper GJ, et al:  The natural history and treatment of Wilms' tumor . Br Med J 1970;;4:195-200.
Bannayan GA, Guvos AG, D'Angio GJ:  Effect of irradiation on the maturation of Wilms' tumor . Cancer 1971;;27:812-818.
Lemerle EM, Tournade M, Gerard-Marchant R, et al:  Wilms' tumor: Natural history and prognostic factors . Cancer 1976;;37:2557-2566.
Silva-Sosa M, Gonzaltez-Carna JL:  Wilms' tumor in children . Prog Clin Cancer 1966;;2:323-334.
Melville RL:  Pitfalls of early diagnosis of spinal cord compression in children . S Afr Med J 1975;;50:621-624.
D'Angio GJ, Beckwith JB, Breslow N, et al:  The results of the Second National Wilms' Tumor Study . Proc Am Soc Clin Oncol 1979;;20:309.
D'Angio GJ, Evans AE, Breslow N, et al:  The treatment of Wilms' tumor: Results of the National Wilms' Tumor Study . Cancer 1976;; 38:633-640.
Gilbert RW, Kim J, Posner JB:  Epidural spinal cord compression from metastatic tumor . Ann Neurol 1978;;3:40-49.
Anderson FM, Carson MJ:  Spinal cord tumors in children . J Pediatr 1953;;43:190-207.
Matson DD, Tachdjian MO:  Intraspinal tumors in infants and children: Review of 115 cases . Postgrad Med 1963;;34:279-295.
Auld A, Buerman A:  Metastatic spinal epidural tumors . Arch Neurol 1966;;15:100-105.
Barron KD, Hirano A, Araki S, et al:  Experiences with metastatic neoplasms involving the spinal cord . Neurology 1959;;9:91-103.
Sellwood RB:  The radiological approach to metastatic cancer of the brain and spine . Br J Radiol 1972;;45:647-653.

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