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Clostridium Infection in Mother and Infant FREE

NANCY E. CHANEY, MD
Am J Dis Child. 1980;134(12):1175-1176. doi:10.1001/archpedi.1980.02130240055018.
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Clostridium infections in newborns, excluding neonatal tetanus, are rarely reported.1-7 The case described here is of special interest because both the mother and infant had classic, symptomatic Clostridium septicemia and both recovered.

Report of a Case.—A 19-hour-old, 3,080-g, female infant was transferred to North Carolina Memorial Hospital (NCMH) because of jaundice, dark urine, and maternal fever. The infant had been delivered by emergency cesarean section for fetal distress of a 25-year-old, O-positive, primagravida after an uncomplicated term pregnancy. An amniotomy performed 2½ hours prior to delivery had yielded clear fluid. Apgar scores were 6 and 5 at one and five minutes, respectively, after birth. Initial tachypnea and grunting had resolved by 1 hour of age. At 12 hours of age, the infant was jaundiced and passing dark urine. Her total serum bilirubin level was 10 mg/dL (direct bilirubin level, 1.0 mg/dL), and hematocrit value 49%. Cord, throat, stool,

REFERENCES

Isenberg AN:  Clostridium welchii infection . Arch Surg 92:727-731, 1966;.
Freedman S, Hollander M:  Clostridium perfringens septicemia as a postoperative complication of the newborn infant . J Pediatr 71:576-578, 1967;.
Wilson WR, Martin WJ, Wilkowske CJ, et al:  Anaerobic bacteremia . Mayo Clin Proc 47:639-646, 1972;.
Walker SH, Macaraeg El:  Neonatal sepsis due to Clostridium perfringens . Md State Med J 22:61-62, 1973;.
Chow AW, Leake RE, Yamauchi T, et al:  The significance of anaerobes in neonatal bacteremia: Analysis of 23 cases and review of the literature . Pediatrics 54:736-745, 1974;.
Gorbach SL, Thadepalli H:  Isolation of Clostridium in human infections: Evaluations of 114 cases . J Infect Dis 131( (suppl) ):S81-S85, 1975;.
Bogdan JC, Rapkin RH:  Clostridia infection in the newborn . Pediatrics 58:120-122, 1976;.
Ramsay AM:  The significance of Clostridium welchii in the cervical swab and blood stream in postpartum and post-abortum sepsis . J Obstet Gynaecol Br Commonw 56:247-258, 1949;.
Rathburn HK:  Clostridial bacteremia without hemolysis . Arch Intern Med 122:496-501, 1968;.
Alpern RJ, Powell VR Jr:  Nonhistotoxic clostridial bacteremia . Am J Clin Pathol 55:717-722, 1971;.
Dunkel LM, Brotherton TJ, Feigin RD:  Anaerobic infections in children: A prospective study . Pediatrics 57:311-320, 1976;.
Kliegman RM, Fanaroff MB, Izant R, et al:  Clostridia as pathogens in neonatal necrotizing enterocolitis . J Pediatr 95:727-731, 1966;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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References

Isenberg AN:  Clostridium welchii infection . Arch Surg 92:727-731, 1966;.
Freedman S, Hollander M:  Clostridium perfringens septicemia as a postoperative complication of the newborn infant . J Pediatr 71:576-578, 1967;.
Wilson WR, Martin WJ, Wilkowske CJ, et al:  Anaerobic bacteremia . Mayo Clin Proc 47:639-646, 1972;.
Walker SH, Macaraeg El:  Neonatal sepsis due to Clostridium perfringens . Md State Med J 22:61-62, 1973;.
Chow AW, Leake RE, Yamauchi T, et al:  The significance of anaerobes in neonatal bacteremia: Analysis of 23 cases and review of the literature . Pediatrics 54:736-745, 1974;.
Gorbach SL, Thadepalli H:  Isolation of Clostridium in human infections: Evaluations of 114 cases . J Infect Dis 131( (suppl) ):S81-S85, 1975;.
Bogdan JC, Rapkin RH:  Clostridia infection in the newborn . Pediatrics 58:120-122, 1976;.
Ramsay AM:  The significance of Clostridium welchii in the cervical swab and blood stream in postpartum and post-abortum sepsis . J Obstet Gynaecol Br Commonw 56:247-258, 1949;.
Rathburn HK:  Clostridial bacteremia without hemolysis . Arch Intern Med 122:496-501, 1968;.
Alpern RJ, Powell VR Jr:  Nonhistotoxic clostridial bacteremia . Am J Clin Pathol 55:717-722, 1971;.
Dunkel LM, Brotherton TJ, Feigin RD:  Anaerobic infections in children: A prospective study . Pediatrics 57:311-320, 1976;.
Kliegman RM, Fanaroff MB, Izant R, et al:  Clostridia as pathogens in neonatal necrotizing enterocolitis . J Pediatr 95:727-731, 1966;.

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