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Article |

Mitogenic Response to Toxocara Antigen and Chemotactic Defect in Visceral Larva Migrans

Kenneth Caldwell, MD; Michael Lobell, MD; Pater F. Coccia, MD
Am J Dis Child. 1980;134(9):845-847. doi:10.1001/archpedi.1980.02130210029008.
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• A 3-year-old girl had the typical features of visceral larva migrans syndrome, including hypereosinophilia, recurrent pulmonary infiltrates, and elevated serum IgG, IgE, and isohemagglutinin titers. A marked mitogenic response of her cultured lymphocytes to Toxocara antigen but not to Ascaris antigen was found. A neutrophil chemotactic abnormality to Escherichia coli culture filtrates and zymosan-activated sera was also demonstrated, which partially corrected after she was treated with diethylcarbamazine citrate.

(Am J Dis Child 134:845-847, 1980)


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