0
Article |

Staphylococcus aureus Sepsis in Childhood Malignancy FREE

James S. Miser, MD; Angela W. Miser, MB, BS
[+] Author Affiliations

Reprint requests to Department of Pediatrics, Columbus Children's Hospital, 700 Children's Dr, Columbus, OH 43205 (Dr J. S. Miser).


Am J Dis Child. 1980;134(9):831-833. doi:10.1001/archpedi.1980.02130210015005.
Text Size: A A A
Published online

• Forty-five episodes of Staphylococcus aureus septicemia occurred in 44 children with malignant neoplasms over a seven-year period. The most frequent findings at diagnosis were fever, neutropenia, and an active malignant process. Twenty-six (58%) of 45 episodes had a primary focus of infection. Multiple-organism sepsis occurred four times; three episodes were fatal. Only one patient with single-organism S aureus sepsis died (a mortality of 2%). Direct infectious complications occurred in nine (20%) of 45 episodes. Endocarditis and osteomyelitis were not seen as complications of S aureus sepsis.

(Am J Dis Child 134:831-833, 1980)

REFERENCES

Hieber JP, Nelson AJ, McCracken GH:  Acute disseminated staphylococcal disease in childhood . Am J Dis Child 131:181-185, 1977;.
Nolan CM, Beaty HN:  Staphylococcus aureus bacteremia: Current clinical patterns . Am J Med 60:495-500, 1976;.
Link to Article
Wise RI:  Modern management of severe staphylococcal disease . Medicine 52:295-304, 1973;.
Link to Article
Allen JD, Roberts CE, Kirby WMM:  Staphylococcal septicemia treated with methicillin . N Engl J Med 266:111-116, 1962;.
Link to Article
Cluff LE, Reynolds RC, Page DL, et al:  Staphylococcal bacteremia and altered host resistance . Ann Intern Med 69:859-873, 1968;.
Link to Article
Faber V, Jessen O, Rosendal K, et al:  Staphylococcal bacteremia: Clinical and bacteriologic observations in 201 cases . Br Med J 2:1832-1837, 1960;.
Link to Article
Chilcote RR, Bachner RL:  Septicemia in association with acute lymphoblastic leukemia . J Pediatr 94:715-718, 1979;.
Link to Article
Ladisch S, Pizzo PA:  Staphylococcus aureus sepsis in children with cancer . Pediatrics 61:231-234, 1978;.
Louria DB, Hensle T, Rose J:  The major complications of heroin addiction . Ann Intern Med 67:1-22, 1967;.
Link to Article
Cherubin CE, Baden M, Kaveler F, et al:  Infective endocarditis in narcotic addicts . Ann Intern Med 69:1091-1098, 1968;.
Link to Article
Iannini PB, Crossley K:  Therapy of Staphylococcus aureus bacteremia associated with a removable focus of infection . Ann Intern Med 84:558-560, 1976;.
Link to Article
MacGregor RR, Beaty HN:  Evaluation of positive blood cultures: Guidelines for early differentiation of contaminated from valid positive cultures . Arch Intern Med 130:84-87, 1972;.
Link to Article
Bauer AW, Kirby WMM, Sherris JC, et al:  Antibiotic susceptibility testing by a standardized single-disk method . Am J Clin Pathol 45:493-495, 1966;.
Richar WJ, Breakwell ES:  Evaluation of an electronic particle counter for the counting of white blood cells . Am J Clin Pathol 31:384-386, 1959;.
Bodey GP:  Infections in cancer patients . Cancer Treat Rev 2:89-128, 1975;.
Link to Article
Shulman ST, Ayoub EM:  Severe staphylococcal sepsis in adolescents . Pediatrics 58:59-66, 1976;.
Wilson R, Hamburger M:  Fifteen years' experience with Staphylococcus septicemia in acute leukemia . Am J Med 22:437-457, 1957;.
Link to Article
Bodey GP, Nies BA, Freireich EJ:  Multiple organism septicemia in acute leukemia . Arch Intern Med 116:266-272, 1965;.
Link to Article
Waldrogel FA, Medoff G, Schwartz MN:  Osteomyelitis: A review of clinical features, therapeutic considerations and unusual aspects . N Engl J Med 282:198-206, 260-268, 316-322, 1970;.
Link to Article
Studdert TC:  Staphylococcal spinal meningitis . Br Med J 1:1457-1459, 1958;.
Link to Article
Swartz MN, Dodge PR:  Bacterial meningitis: A review of selected aspects . N Engl J Med 272:779-787, 1965;.
Link to Article
Highman JH:  Staphylococcal pneumonia and empyema in childhood . Amer J Roentgen 106:103-108, 1969;.
Link to Article
Miller WR, Jay AR:  Staphylococcal pneumonia in influenza: Five cases . Arch Intern Med 109:276-286, 1962;.
Link to Article
Wise MB, Beaudry PH, Bates DV:  Long-term follow-up of staphylococcal pneumonia . Pediatrics 38:398-401, 1966;.
Anand SV, Evans KT:  Pyomyositis . Br J Surg 51:917-920, 1964;.
Link to Article
Melish ME, Glasgow LA:  Staphylococcalscaled skin syndrome: The expanded clinical syndrome . J Pediatr 78:958-967, 1971;.
Link to Article

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

Hieber JP, Nelson AJ, McCracken GH:  Acute disseminated staphylococcal disease in childhood . Am J Dis Child 131:181-185, 1977;.
Nolan CM, Beaty HN:  Staphylococcus aureus bacteremia: Current clinical patterns . Am J Med 60:495-500, 1976;.
Link to Article
Wise RI:  Modern management of severe staphylococcal disease . Medicine 52:295-304, 1973;.
Link to Article
Allen JD, Roberts CE, Kirby WMM:  Staphylococcal septicemia treated with methicillin . N Engl J Med 266:111-116, 1962;.
Link to Article
Cluff LE, Reynolds RC, Page DL, et al:  Staphylococcal bacteremia and altered host resistance . Ann Intern Med 69:859-873, 1968;.
Link to Article
Faber V, Jessen O, Rosendal K, et al:  Staphylococcal bacteremia: Clinical and bacteriologic observations in 201 cases . Br Med J 2:1832-1837, 1960;.
Link to Article
Chilcote RR, Bachner RL:  Septicemia in association with acute lymphoblastic leukemia . J Pediatr 94:715-718, 1979;.
Link to Article
Ladisch S, Pizzo PA:  Staphylococcus aureus sepsis in children with cancer . Pediatrics 61:231-234, 1978;.
Louria DB, Hensle T, Rose J:  The major complications of heroin addiction . Ann Intern Med 67:1-22, 1967;.
Link to Article
Cherubin CE, Baden M, Kaveler F, et al:  Infective endocarditis in narcotic addicts . Ann Intern Med 69:1091-1098, 1968;.
Link to Article
Iannini PB, Crossley K:  Therapy of Staphylococcus aureus bacteremia associated with a removable focus of infection . Ann Intern Med 84:558-560, 1976;.
Link to Article
MacGregor RR, Beaty HN:  Evaluation of positive blood cultures: Guidelines for early differentiation of contaminated from valid positive cultures . Arch Intern Med 130:84-87, 1972;.
Link to Article
Bauer AW, Kirby WMM, Sherris JC, et al:  Antibiotic susceptibility testing by a standardized single-disk method . Am J Clin Pathol 45:493-495, 1966;.
Richar WJ, Breakwell ES:  Evaluation of an electronic particle counter for the counting of white blood cells . Am J Clin Pathol 31:384-386, 1959;.
Bodey GP:  Infections in cancer patients . Cancer Treat Rev 2:89-128, 1975;.
Link to Article
Shulman ST, Ayoub EM:  Severe staphylococcal sepsis in adolescents . Pediatrics 58:59-66, 1976;.
Wilson R, Hamburger M:  Fifteen years' experience with Staphylococcus septicemia in acute leukemia . Am J Med 22:437-457, 1957;.
Link to Article
Bodey GP, Nies BA, Freireich EJ:  Multiple organism septicemia in acute leukemia . Arch Intern Med 116:266-272, 1965;.
Link to Article
Waldrogel FA, Medoff G, Schwartz MN:  Osteomyelitis: A review of clinical features, therapeutic considerations and unusual aspects . N Engl J Med 282:198-206, 260-268, 316-322, 1970;.
Link to Article
Studdert TC:  Staphylococcal spinal meningitis . Br Med J 1:1457-1459, 1958;.
Link to Article
Swartz MN, Dodge PR:  Bacterial meningitis: A review of selected aspects . N Engl J Med 272:779-787, 1965;.
Link to Article
Highman JH:  Staphylococcal pneumonia and empyema in childhood . Amer J Roentgen 106:103-108, 1969;.
Link to Article
Miller WR, Jay AR:  Staphylococcal pneumonia in influenza: Five cases . Arch Intern Med 109:276-286, 1962;.
Link to Article
Wise MB, Beaudry PH, Bates DV:  Long-term follow-up of staphylococcal pneumonia . Pediatrics 38:398-401, 1966;.
Anand SV, Evans KT:  Pyomyositis . Br J Surg 51:917-920, 1964;.
Link to Article
Melish ME, Glasgow LA:  Staphylococcalscaled skin syndrome: The expanded clinical syndrome . J Pediatr 78:958-967, 1971;.
Link to Article

Correspondence

CME
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.