Ring Chromosome 15 and Failure to Thrive FREE

BORIS G. KOUSSEFF, MD

Am J Dis Child. 1980;134(8):798-799. doi:10.1001/archpedi.1980.02130200066022.

Text Size: A A A

Published online

Article

References

Comments

ABSTRACT

ABSTRACT | REFERENCES

Ring chromosomes are rare in man. Friedrich and Nielson¹ could not find one ring in the compiled data of the cytogenetic screening of 31,801 consecutive live-born children. Hecht and Vlietinck,² as well as Zdansky et al,³ claim that the phenotypic and cytogenetic differences among even "identical rings" do not permit an accurate delineation of an identifiable syndrome. On the other hand, certain ring chromosome syndromes (ring 1, 6, 9,13, 15, 21, and 22) appear already in textbooks⁴ as separate clinical entities. To solve the controversy, more case reports seem warranted. Therefore, we discuss an infant with ring 15.

Report of a Case.—This girl was a product of the second pregnancy for her mother, who was 161 cm tall and 27 years of age at that time. The father was 168 cm tall and 35 years of age. Illness, exposure to drugs, and roentgenograms during the pregnancy were

REFERENCES

ABSTRACT | REFERENCES

Friedrich U, Nielson J: Chromosome studies in 5,049 consecutive newborn children . Clin Genet 4:333-343, 1973;.
Link to Article

Hecht F, Vlietinck RF: Autosomal rings and variable phenotypes . Hum Genet 18:99-100, 1973;.
Link to Article

Zdansky R, Andre M, Bühler E, et al: Irregular phenotypic expression of ring chromosomes . Hum Genet 16:193-198, 1975;.

DeGrouchy J, Turleau C: Clinical Atlas of Human Chromosomes . New York, John Wiley & Sons, 1977;.

Jacobsen P: A ring chromosome in the 13-15 group associated with microcephalic dwarfism, mental retardation and emotional immaturity . Hereditas 55:188-191, 1966;.
Link to Article

Emberger JM, Rossi D, Jean R, et al: Etude d'une observation de chromosome du group 13-15 en anneau (46,XY, 15r) . Hum Genet 11:295-299, 1971;.
Link to Article

Forabosco A, Dutrillaux B, Vazzoler G, et al: Chromosome 15 en anneau; r(15): Identification a dénuturation ménageé . Ann Genet 15:267-270, 1972;.

Stoll C, Juif JG, Luckel JC, et al: Ring chromosome 15:r(15): Identification by R banding . Hum Genet 27:259-262, 1975;.
Link to Article

Rumenić L, Joksimović I, Anaf M: Ring chromosome 15 in child with a minor dysmorphism of phenotype . Hum Genet 33:187-188, 1976;.
Link to Article

Pfeiffer RA, Dhadial R, Lenz W: 46,XX/46,XX,r(15) mosaicism: Report of a case . J Med Genet 14:63-65, 1977;.
Link to Article

Schmid M, Henrichs I, Nestler H, et al: Analysis of banding patterns and mosaic configurations in a case of ring chromosome 15 . Hum Genet 41:289-299, 1978;.
Link to Article

Fujita H, Matsomoto H: Ring chromosome 15; 46,XX,r(15) (p11q26) in a girl . Jpn J Hum Genet 23:233-237, 1978;.
Link to Article

Kawasaki T, Kamimae A, Maeda J, et al: A case with No. 15 ring chromosome (Japanese) . J Pediatr Prac 38:544, 1975;.

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal