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June 1980, Vol 134, No. 6 >
Article | June 1980

Herpes Zoster in Early Infancy FREE

MEYER DWORSKY, MD; RICHARD WHITLEY, MD; CHARLES ALFORD, MD
Am J Dis Child. 1980;134(6):618-619. doi:10.1001/archpedi.1980.02130180074021.
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Maternal chickenpox may result in one of the following two major clinical syndromes: early onset postnatal chickenpox or intrauterine infection.1-2 Infection in the susceptible female early in gestation may rarely lead to severely affected infants who may display multiple congenital anomalies, as described in several similar case reports.3-5

Dermatomal localization, the sine qua non of shingles, has been a prominent feature of some of the case reports of the severely affected neonates as well as of a few cases of isolated disease early in life. This report documents the cases of two infants who had shingles during the first few months of life after intrauterine exposure to varicella-zoster virus.

Materials and Methods.—Standard virological procedures were used for the identification and isolation of varicella-zoster virus. Levels of complement-fixing anti-body to varicella-zoster virus were determined by the methodology described by Brunell and Casey.6 Immunofluorescence antibody was determined

REFERENCES

1 +
Meyer JD:  Congenital varicella in term infants: Risk reconsidered . J Infect Dis 129:215-218, 1974;.
2 +
Gershon AA:  Varicella in mother and infant , in Krugman S, Gershon AA (eds): Infections of the Fetus and Newborn: Progress in Clinical and Virological Research . New York, Alan R. Liss Inc, 1975;, vol 3, pp 79-96.
3 +
Srabstein JC, Morris N, Larke RPB, et al:  Is there a congenital varicella syndrome? J Pediatr 84:239-243, 1974;.
4 +
Dodion-Fransen J, Dekegel D, Thiry L:  Congenital varicella-zoster infection related to maternal disease in early pregnancy . Scand J Infect Dis 5:149-153, 1973;.
5 +
Bai PVA, John TJ:  Congenital skin ulcers following varicella in late pregnancy . J Pediatr 94:65-68, 1979;.
6 +
Brunell PA, Casey HL:  Crude tissue culture antigen for determination of varicella-zoster complement-fixing antibody . Public Health Rep 79:839-942, 1964;.
7 +
Mazur MH, Whitley RJ, Dolin R:  Serum antibody levels as risk factors in the dissemination of herpes zoster . Ann Intern Med 139:1341-1345, 1979;.
8 +
Lyday JH:  Report of severe herpes zoster in a 13½-year-old boy whose chickenpox infection may have been acquired in utero . Pediatrics 50:930-931, 1972;.
9 +
Brunell PA, Miller LH, Lovejoy F:  Zoster in children . Am J Dis Child 115:432-437, 1968;.
10 +
McKendrick GDW, Raychoudhury SC:  Herpes zoster in childhood . Scand J Infect Dis 4:23-25, 1972;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Meyer JD:  Congenital varicella in term infants: Risk reconsidered . J Infect Dis 129:215-218, 1974;.
2 +
Gershon AA:  Varicella in mother and infant , in Krugman S, Gershon AA (eds): Infections of the Fetus and Newborn: Progress in Clinical and Virological Research . New York, Alan R. Liss Inc, 1975;, vol 3, pp 79-96.
3 +
Srabstein JC, Morris N, Larke RPB, et al:  Is there a congenital varicella syndrome? J Pediatr 84:239-243, 1974;.
4 +
Dodion-Fransen J, Dekegel D, Thiry L:  Congenital varicella-zoster infection related to maternal disease in early pregnancy . Scand J Infect Dis 5:149-153, 1973;.
5 +
Bai PVA, John TJ:  Congenital skin ulcers following varicella in late pregnancy . J Pediatr 94:65-68, 1979;.
6 +
Brunell PA, Casey HL:  Crude tissue culture antigen for determination of varicella-zoster complement-fixing antibody . Public Health Rep 79:839-942, 1964;.
7 +
Mazur MH, Whitley RJ, Dolin R:  Serum antibody levels as risk factors in the dissemination of herpes zoster . Ann Intern Med 139:1341-1345, 1979;.
8 +
Lyday JH:  Report of severe herpes zoster in a 13½-year-old boy whose chickenpox infection may have been acquired in utero . Pediatrics 50:930-931, 1972;.
9 +
Brunell PA, Miller LH, Lovejoy F:  Zoster in children . Am J Dis Child 115:432-437, 1968;.
10 +
McKendrick GDW, Raychoudhury SC:  Herpes zoster in childhood . Scand J Infect Dis 4:23-25, 1972;.

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