We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Nosocomial Pertussis: A Failure of Erythromycin Treatment and Prophylaxis

Am J Dis Child. 1980;134(5):521-522. doi:10.1001/archpedi.1980.02130170071024.
Text Size: A A A
Published online


A variety of antimicrobial agents have been used to treat children with pertussis to decrease the excretion of Bordetella pertussis and we hope prevent transmission of the infection to other children.1-5 Erythromycin is considered the drug of choice for B pertussis infections by the American See also p 520. Academy of Pediatrics Committee on Infectious Disease because of its low toxicity and superior efficacy in eradicating this organism from the nasopharynx when compared with other antimicrobial agents.3-7

We report the failure of seven days of erythromycin therapy to eradicate B pertussis from the pharynx of an infant. A second infant who was exposed to this child also contracted pertussis in spite of prophylactic use of erythromycin.

Bacteriologic Methods.—Nasal washing specimens were cultured and examined by direct fluorescent antibody (FA) techniques. Fresh control slides were prepared for each FA examination using stock B pertussis and B parapertussis cultures.


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.