0
May 1980, Vol 134, No. 5 >
Article | May 1980

New Thoughts on Aspirin FREE

JOHN BAUM, MD
Am J Dis Child. 1980;134(5):455. doi:10.1001/archpedi.1980.02130170005002.
Text Size: A A A
Published online
Article
References
Comments

Aspirin continues to hold its place as a cheap and effective way of treating patients with juvenile arthritis. The article by Doughty and his colleagues in this issue (p 461) reiterates aspirin's effectiveness and gives us a number of practical points in its usage.

Although rheumatologists (and Jane Schaller recently for children1) have often pointed out the desirability of maintaining serum salicylate levels between 20 and 30 mg/dL, this report satisfactorily establishes these limits. Most important is the upper limit where the authors have shown that there is no significant improvement in clinical response with salicylate levels higher than 30 mg/dL. When other nonsteroidal anti-inflammatory drugs were not available for the treatment of juvenile arthritis, it was thought to be worthwhile to try to push aspirin levels higher than 30 mg/dL. However, with the availability of at least one of the newer agents, tolmetin sodium,2 it probably is inadvisable

REFERENCES

1 +
Schaller JG:  Chronic salicylate administration in juvenile rheumatoid arthritis: Aspirin "hepatitis" and its clinical significance . Pediatrics 62:916-925, 1978;.
2 +
Levinson JE, Baum J, Brewer E, et al:  Comparison of tolmetin sodium and aspirin in the treatment of juvenile rheumatoid arthritis . J Pediatr 91:799-804, 1977;.
3 +
Makela AL, Yrjana T, Mattila M:  Dosage of salicylates for children with juvenile rheumatoid arthritis . Acta Pediatr Scand 68:423-430, 1979;.
4 +
Silvoso GR, Ivey KJ, Butt JH, et al:  Incidence of gastric lesions in patients with rheumatic disease on chronic aspirin therapy . Ann Intern Med 91:517-520, 1979;.
5 +
Orozco-Alcala JJ, Baum J:  Regular and enteric coated aspirin: A reevaluation . Arthritis Rheum 22:1034-1037, 1979;.

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Schaller JG:  Chronic salicylate administration in juvenile rheumatoid arthritis: Aspirin "hepatitis" and its clinical significance . Pediatrics 62:916-925, 1978;.
2 +
Levinson JE, Baum J, Brewer E, et al:  Comparison of tolmetin sodium and aspirin in the treatment of juvenile rheumatoid arthritis . J Pediatr 91:799-804, 1977;.
3 +
Makela AL, Yrjana T, Mattila M:  Dosage of salicylates for children with juvenile rheumatoid arthritis . Acta Pediatr Scand 68:423-430, 1979;.
4 +
Silvoso GR, Ivey KJ, Butt JH, et al:  Incidence of gastric lesions in patients with rheumatic disease on chronic aspirin therapy . Ann Intern Med 91:517-520, 1979;.
5 +
Orozco-Alcala JJ, Baum J:  Regular and enteric coated aspirin: A reevaluation . Arthritis Rheum 22:1034-1037, 1979;.

Correspondence

Submit a Letter
CME
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Clear Answers | Save For Later
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Compression-Only CPR: Pushing the Science Forward
Cone
AAM 2010;304:1493-1495.
All you need to read in the other general journals
BMJ 2010;341:c5893-c1494.
Submit a Comment

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

© 2013 American Medical Association. All Rights Reserved.
Powered bySilverchair Information Systems