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Nasal Polymorphic Reticulosis in a Child FREE

Donald C. Houghton, MD; Eugene Blank, MD; James D. Smith, DVM, MD
[+] Author Affiliations

Reprint requests to Department of Pathology, University of Oregon Health Sciences Center, 3181 SW Sam Jackson Park Rd, Portland, OR 97201 (Dr Houghton).


Am J Dis Child. 1980;134(4):387-389. doi:10.1001/archpedi.1980.04490010041014.
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• The case of nasal polymorphic reticulosis in a child is presented. The patient, an 11-year-old adopted boy, complained of nasal stuffiness and pain. Perforation of the nasal septum and ulceration of the hard palate were evident on examination, and an irregular tumor in the nasal cavity was demonstrated by tomography. Biopsy specimen showed atypical lymphoreticular cells within mixed inflammatory infiltrates. He was treated with radiation followed by cyclophosphamide, mercaptopurine, and methotrexate sodium. Despite regression of the palate lesion and a 12-month symptom-free interval, he died of disseminated polymorphic reticulosis 1½ years after diagnosis. We are unable to find a similar reported case in a child.

(Am J Dis Child 134:387-389, 1980)

REFERENCES

Eichel BS, Harrison EG Jr, Devine KD, et al:  Primary lymphoma of the nose including a relationship to lethal midline granuloma . J Surg 112:597-605, 1966;.
Kassel SH, Echevarria RA, Guezzo FP:  Midline malignant reticulosis . Cancer 23:920-935, 1969;.
McGuirt WF, Rose EF:  Lethal midline granuloma: A pathological spectrum . J Laryngol Otol 90:459-466, 1976;.
Stewart JP:  Progressive lethal granulomatous ulceration of the nose . J Laryngol Otol 48:657-701, 1933;.
Askin FB:  Nose, nasopharynx, larynx and trachea , in Kissane JM (ed): Pathology of Infancy and Childhood , ed 2. St Louis, CV Mosby Co, 1975;, p 451.
Jaffe BF:  Pediatric head and neck tumors: A study of 178 cases . Laryngoscope 83:1644-1651, 1973;.
Roback SA, Herdman RC, Hoyer J, et al:  Wegener's granulomatosis in a child . Am J Dis Child 118:608-614, 1969;.
Michaels L, Gregory MM:  Pathology of 'nonhealing (midline) granuloma.' J Clin Pathol 30:317-327, 1977;.
Friedman I, Sando I, Bakany TH:  Idiopathic pleomorphic midfacial granuloma (Stewarts type) . J Laryngol Otol 92:601-611, 1978;.
Douglas AC, Anderson TJ, MacDonald M:  Midline and Wegener's granulomatosis . Ann NY Acad Sci 278:618-635, 1976;.
Fechner RE, Lamppin DW:  Midline malignant reticulosis: A clinicopathologic entity . Arch Otolaryngol 95:467-476, 1972;.
McDonald TJ, DeRemee RA, Harrison EG Jr, et al:  The protean clinical features of polymorphic reticulosis (lethal midline granuloma) . Laryngoscope 86:936-945, 1976;.
McGuirt FW, Rose EF:  Lethal midline granuloma: A pathological spectrum . J Laryngol Otol 90:459-466, 1976;.
Yesus YW:  Midline malignant reticulosis: Case report . Mo Med 74:375-378, 1977;.

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References

Eichel BS, Harrison EG Jr, Devine KD, et al:  Primary lymphoma of the nose including a relationship to lethal midline granuloma . J Surg 112:597-605, 1966;.
Kassel SH, Echevarria RA, Guezzo FP:  Midline malignant reticulosis . Cancer 23:920-935, 1969;.
McGuirt WF, Rose EF:  Lethal midline granuloma: A pathological spectrum . J Laryngol Otol 90:459-466, 1976;.
Stewart JP:  Progressive lethal granulomatous ulceration of the nose . J Laryngol Otol 48:657-701, 1933;.
Askin FB:  Nose, nasopharynx, larynx and trachea , in Kissane JM (ed): Pathology of Infancy and Childhood , ed 2. St Louis, CV Mosby Co, 1975;, p 451.
Jaffe BF:  Pediatric head and neck tumors: A study of 178 cases . Laryngoscope 83:1644-1651, 1973;.
Roback SA, Herdman RC, Hoyer J, et al:  Wegener's granulomatosis in a child . Am J Dis Child 118:608-614, 1969;.
Michaels L, Gregory MM:  Pathology of 'nonhealing (midline) granuloma.' J Clin Pathol 30:317-327, 1977;.
Friedman I, Sando I, Bakany TH:  Idiopathic pleomorphic midfacial granuloma (Stewarts type) . J Laryngol Otol 92:601-611, 1978;.
Douglas AC, Anderson TJ, MacDonald M:  Midline and Wegener's granulomatosis . Ann NY Acad Sci 278:618-635, 1976;.
Fechner RE, Lamppin DW:  Midline malignant reticulosis: A clinicopathologic entity . Arch Otolaryngol 95:467-476, 1972;.
McDonald TJ, DeRemee RA, Harrison EG Jr, et al:  The protean clinical features of polymorphic reticulosis (lethal midline granuloma) . Laryngoscope 86:936-945, 1976;.
McGuirt FW, Rose EF:  Lethal midline granuloma: A pathological spectrum . J Laryngol Otol 90:459-466, 1976;.
Yesus YW:  Midline malignant reticulosis: Case report . Mo Med 74:375-378, 1977;.

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