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February 1980, Vol 134, No. 2 >
Article | February 1980

Necrotizing Enterocolitis FREE

HERBERT GOLDMAN, MD
Am J Dis Child. 1980;134(2):207. doi:10.1001/archpedi.1980.02130140077024.
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Sir.—I read with interest the article "Epidemic Occurrence of Neonatal Necrotizing Enterocolitis," by Guinan et al (Journal 133:594-597, 1979). The observation that almost all infants (38 of 39) were fed prior to the onset of necrotizing enterocolitis (NEC) is in agreement with other studies.1-5 In one retrospective, case-control study similar in design to that of Guinan et al, 54 of 54 infants were fed prior to NEC onset, whereas only 63% of 98 matched controls (P <.001) were fed at a comparable time.2 These findings strongly suggest an etiologic relationship between feeding and NEC. Guinan et al do not tell us how many of their controls were fed, and this would be a statistic of some interest.

In an unpublished survey carried out in the early 1960s of feeding practices in six premature nurseries in the metropolitan New York City area, I found that slow, gradual feeding

REFERENCES

1 +
Santulli TV, Schullinger JN, Heird WC, et al:  Acute necrotizing enterocolitis in infancy: A review of 64 cases . Pediatrics 55:376-385, 1975;.
2 +
Frantz ID, L'Heureux P, Engel RR, et al:  Necrotizing enterocolitis . J Pediatr 86:259-263, 1975;.
3 +
Roty AR, Kilway JB, Brown AL:  Acute necrotizing enterocolitis in neonates . Am Surg 43:392-394, 1977;.
4 +
Bell RS, Graham CB, Stevenson JK:  Roentgenologic and clinical manifestations of neonatal necrotizing enterocolitis . Am J Roentgenol Radium Ther Nucl Med 112:123-127, 1971;.
5 +
Krouskop RW, Brown EG, Sweet AY:  The relationship of feeding to necrotizing enterocolitis, abstracted . Pediatr Res 8:383, 1974;.
6 +
Terris M: Goldberger on Pellagra . Baton Rouge, La, Louisiana State University Press, 1964;, pp 10-11.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Santulli TV, Schullinger JN, Heird WC, et al:  Acute necrotizing enterocolitis in infancy: A review of 64 cases . Pediatrics 55:376-385, 1975;.
2 +
Frantz ID, L'Heureux P, Engel RR, et al:  Necrotizing enterocolitis . J Pediatr 86:259-263, 1975;.
3 +
Roty AR, Kilway JB, Brown AL:  Acute necrotizing enterocolitis in neonates . Am Surg 43:392-394, 1977;.
4 +
Bell RS, Graham CB, Stevenson JK:  Roentgenologic and clinical manifestations of neonatal necrotizing enterocolitis . Am J Roentgenol Radium Ther Nucl Med 112:123-127, 1971;.
5 +
Krouskop RW, Brown EG, Sweet AY:  The relationship of feeding to necrotizing enterocolitis, abstracted . Pediatr Res 8:383, 1974;.
6 +
Terris M: Goldberger on Pellagra . Baton Rouge, La, Louisiana State University Press, 1964;, pp 10-11.

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