Although a frequent roentgenographic observation in elderly persons,1 linear calcification of the ascending aorta is extremely rare in infancy and childhood. Our purpose is to report linear calcification of the ascending aorta in an adolescent in whom extensive investigations failed to establish causal basis for the lesion.
Report of a Case.—The patient, a 12-year-old girl, was the result of an uncomplicated pregnancy and a full-term spontaneous delivery. Her birth weight was 3.4 kg. There was no family history of congenital heart disease, vascular disease, or candidiasis. She remained perfectly well until 9 months of age when, after an upper respiratory tract infection, oral thrush developed. Candida albicans grew from cultures of material obtained from the oral lesions. Despite antifungal treatment—first with nystatin (Mycostatin) and later with amphotericin B—the mucocutaneous lesions spread and, during the next four years, involved the arms, legs, both ears, and all fingernails and