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June 1979, Vol 133, No. 6 >
Article | June 1979

Prosthetic Valve Endocarditis due to Haemophilus parainfluenzae Biotype II FREE

Donald C. Blair, MD; Leonard B. Weiner, MD
[+] Author Affiliations

Reprint requests to Department of Pediatrics, Upstate Medical Center, 750 E Adams St, Syracuse, NY 13210 (Dr Weiner).


Am J Dis Child. 1979;133(6):617-618. doi:10.1001/archpedi.1979.02130060057011.
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• Haemophilus parainfluenzae endocarditis is characterized by great variation in the acuteness of presentation, difficulty in isolation of the pathogen, a 50% to 60% incidence of major arterial emboli, and variability of response to therapy. Prosthetic valve endocarditis (PVE) due to H parainfluenzae biotype II occurred in a 14-year-old girl with congenital heart disease and a Starr-Edwards mitral valve prosthesis. Management was complicated by a prolonged culture-negative period (eight days), intermittent bacteremia (only five of 15 positive blood cultures), an embolus to the right femoral artery, progressive congestive heart failure, and urgent prosthetic valve replacement. Cure was achieved with 44 days of ampicillin sodium-gentamicin sulfate therapy monitored by serum bactericidal titers.

(Am J Dis Child 133:617-618, 1979)

REFERENCES

1 +
Geraci JE, Wilkowske CJ, Wilson WR, et al:  Haemophilus endocarditis: Report of 14 patients . Mayo Clinic Proc 52:209-215, 1977;.
2 +
Goldsweig HG, Matsen JM, Castaneda AR:  Haemophilus aphrophilus endocarditis in a patient with a valve prosthesis . J Thorac Cardiovasc Surg 63:408-411, 1972;.
3 +
Chunn CJ, Jones SR, McCutchan JA, et al:  Haemophilus parainfluenzae infective endocarditis . Medicine 56:99-113, 1977;.
4 +
Blair DC, Walker W, Sodeman T, et al:  Bacterial endocarditis due to Haemophilus parainfluenzae . Chest 71:146-149, 1977;.
5 +
Lynn DJ, Kane JG, Parker RH:  Haemophilus parainfluenzae and influenzae endocarditis: A review of 40 cases . Medicine 56:115-128, 1977;.
6 +
Dahlgren J, Tally FP, Brothers G, et al:  Haemophilus parainfluenzae endocarditis . Am J Clin Pathol 62:607-611, 1974;.
7 +
Weinstein L, Rubin RH:  Infective endocarditis—1973 . Prog Cardiovasc Dis 16:239-274, 1973;.
8 +
Mayo JB, McCarthy LR:  Antimicrobial susceptibility of Haemophilus parainfluenzae . Antimicrob Agents Chemother 11:844-847, 1977;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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References

1 +
Geraci JE, Wilkowske CJ, Wilson WR, et al:  Haemophilus endocarditis: Report of 14 patients . Mayo Clinic Proc 52:209-215, 1977;.
2 +
Goldsweig HG, Matsen JM, Castaneda AR:  Haemophilus aphrophilus endocarditis in a patient with a valve prosthesis . J Thorac Cardiovasc Surg 63:408-411, 1972;.
3 +
Chunn CJ, Jones SR, McCutchan JA, et al:  Haemophilus parainfluenzae infective endocarditis . Medicine 56:99-113, 1977;.
4 +
Blair DC, Walker W, Sodeman T, et al:  Bacterial endocarditis due to Haemophilus parainfluenzae . Chest 71:146-149, 1977;.
5 +
Lynn DJ, Kane JG, Parker RH:  Haemophilus parainfluenzae and influenzae endocarditis: A review of 40 cases . Medicine 56:115-128, 1977;.
6 +
Dahlgren J, Tally FP, Brothers G, et al:  Haemophilus parainfluenzae endocarditis . Am J Clin Pathol 62:607-611, 1974;.
7 +
Weinstein L, Rubin RH:  Infective endocarditis—1973 . Prog Cardiovasc Dis 16:239-274, 1973;.
8 +
Mayo JB, McCarthy LR:  Antimicrobial susceptibility of Haemophilus parainfluenzae . Antimicrob Agents Chemother 11:844-847, 1977;.

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