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Miliary Tuberculosis in Children:  Clinical and Laboratory Manifestations in 19 Patients FREE

Kenneth E. Schuit, MD, PhD
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Am J Dis Child. 1979;133(6):583-585. doi:10.1001/archpedi.1979.02130060023003.
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• The clinical course of 19 children with miliary tuberculosis was studied. Complaints were nonspecific and included fever, anorexia, weight loss, and night sweats. Although all but one child had a miliary infiltrate visible on the chest roentgenogram, only 13 had a positive reaction to the purified protein derivative of tuberculin test at admission to the hospital. Outcome was excellent unless the child also had tuberculous meningitis or was in a far advanced state of the disease. Miliary tuberculosis continues to be a rare but important cause of illness in the pediatric population. Seriously ill children with undiagnosed conditions of febrile disease deserve an aggressive evaluation for miliary tuberculosis, including an epidemiological survey, serial chest roentgenograms, and extensive, repeated culturing.

(Am J Dis Child 133:583-585, 1979)

REFERENCES

Munt P:  Miliary tuberculosis in the chemotherapy era: With a clinical review in 69 American adults . Medicine 51:139-155, 1971;.
Jacques J, Sloan JM:  The changing pattern of miliary tuberculosis . Thorax 25:237-240, 1970;.
 Miliary tuberculosis: A changing pattern, editorial . Lancet 1:985-986, 1970;.
Lincoln EM, Hould F:  Results of specific treatment of miliary tuberculosis in children . N Engl J Med 261:113-120, 1959;.
Lorber J:  The long-term prognosis of generalized miliary tuberculosis in children . Lancet 1:1447-1449, 1966;.
Steiner P, Rao M, Victoria MS, et al:  Miliary tuberculosis in two infants after nursery exposure: Epidemiologic, clinical, and laboratory findings . Am Rev Respir Dis 113:267-271, 1976;.
Lorber J:  Tuberculous iridocyclitis and sclerokeratitis followed by tuberculous meningitis and miliary tuberculosis in an infant . Proc R Soc Med 60:894, 1967;.
Sahn SA, Neff TA:  Miliary tuberculosis . Am J Med 56:495-505, 1974;.
Proudfoot AT, Akhtar AJ, Douglas AC, et al:  Miliary tuberculosis in adults . Br Med J 2:273-276, 1969;.
Bottiger LE, Nordenstam HH, Wester PO:  Disseminated tuberculosis as a cause of fever of obscure origin . Lancet 1:19, 1962;.
McClung HJ:  Prolonged fever of unknown origin in children . Am J Dis Child 124:544-550, 1972;.
Pizzo PA, Lovejoy FH, Smith DH:  Prolonged fever in children: Review of 100 cases . Pediatrics 55:468-473, 1975;.
Felson A:  Acute miliary diseases of the lung . Radiology 59:32-48, 1952;.

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References

Munt P:  Miliary tuberculosis in the chemotherapy era: With a clinical review in 69 American adults . Medicine 51:139-155, 1971;.
Jacques J, Sloan JM:  The changing pattern of miliary tuberculosis . Thorax 25:237-240, 1970;.
 Miliary tuberculosis: A changing pattern, editorial . Lancet 1:985-986, 1970;.
Lincoln EM, Hould F:  Results of specific treatment of miliary tuberculosis in children . N Engl J Med 261:113-120, 1959;.
Lorber J:  The long-term prognosis of generalized miliary tuberculosis in children . Lancet 1:1447-1449, 1966;.
Steiner P, Rao M, Victoria MS, et al:  Miliary tuberculosis in two infants after nursery exposure: Epidemiologic, clinical, and laboratory findings . Am Rev Respir Dis 113:267-271, 1976;.
Lorber J:  Tuberculous iridocyclitis and sclerokeratitis followed by tuberculous meningitis and miliary tuberculosis in an infant . Proc R Soc Med 60:894, 1967;.
Sahn SA, Neff TA:  Miliary tuberculosis . Am J Med 56:495-505, 1974;.
Proudfoot AT, Akhtar AJ, Douglas AC, et al:  Miliary tuberculosis in adults . Br Med J 2:273-276, 1969;.
Bottiger LE, Nordenstam HH, Wester PO:  Disseminated tuberculosis as a cause of fever of obscure origin . Lancet 1:19, 1962;.
McClung HJ:  Prolonged fever of unknown origin in children . Am J Dis Child 124:544-550, 1972;.
Pizzo PA, Lovejoy FH, Smith DH:  Prolonged fever in children: Review of 100 cases . Pediatrics 55:468-473, 1975;.
Felson A:  Acute miliary diseases of the lung . Radiology 59:32-48, 1952;.

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