Chronic Nonspecific Diarrhea: A Complication of Dietary Fat Restriction FREE

Stanley A. Cohen, MD; Kristy M. Hendricks, RD; Edmund J. Eastham, MB; Richard K. Mathis, MD; W. Allan Walker, MD

Presented in part at the plenary session of the Society for Pediatric Research, New York, April 27, 1978.

Reprint requests to Pediatric Gastrointestinal and Nutrition Unit, Massachusetts General Hospital, Boston, MA 02114 (Dr Cohen).

Am J Dis Child. 1979;133(5):490-492. doi:10.1001/archpedi.1979.02130050034007.

Text Size: A A A

Published online

Article

References

Comments

ABSTRACT

ABSTRACT | REFERENCES

• Chronic nonspecific diarrhea is a frequent cause of prolonged diarrhea in childhood. Typical diagnostic features include onset by 30 months of age, normal growth and development, and diarrhea lasting longer than two weeks. It usually follows gastroenteritis or an acute infection and has been associated with a low intake of dietary fat. Five patients experienced this condition following dietary manipulation to prevent the occurrence of atheromatous coronary artery disease. This indicates that diminished dietary fat not only can prolong postinfectious diarrhea but can also induce a state of chronic diarrhea without evidence of malabsorption.

(Am J Dis Child 133:490-492, 1979)

REFERENCES

ABSTRACT | REFERENCES

Wender E, Palmer F, Herbst J, et al: Behavioral characteristics of children with chronic nonspecific diarrhea . Am J Psychiatry 113:20-25, 1976;.

Harries J: Essentials of Pediatric Gastroenterology . Edinburgh, Scotland, Churchill Livingstone, 1977;, pp 240-242.

Werlin S: Chronic nonspecific diarrhea , in Hoekelman RA, Blatman S, Brunell PA (eds): Principles of Pediatrics . New York, McGraw-Hill Book Co Inc, 1978;, pp 842-843.

Cohen S, Mathis R, Walker WA: Chronic nonspecific diarrhea: Role of dietary management in control . Pediatr Res 12:432, 1978;.

Roy C, Silverman A: Pediatric-Clinical Gastroenterology . St Louis, The CV Mosby Co Publishers, 1975;, pp 195-197.

Davidson M: The celiac syndrome . Pediatrics 21:508-511, 1958;.

Prugh DG, Shwachman H: Observation on "unexplained" chronic diarrhea in early childhood . Am J Dis Child 90:496-500, 1955;.

Cohlan S: Chronic nonspecific diarrhea in infants and children treated with diiodohydroxyquinoline . Pediatrics 18:424-432, 1956;.

Davidson M, Waserman R: The irritable colon of childhood (chronic nonspecific diarrhea syndrome) . J Pediatr 60:1027-1038, 1966;.

Cohen S, Lake A, Mathis R, et al: Perspectives on chronic nonspecific diarrhea: Dietary management . Pediatrics 61:808-809, 1978;.

Mann GV: Diet-heart: End of an era . N Engl J Med 297:644-648, 1977;.

Larsen R, Glueck CJ, Tsang R: Special diet for familial type II hyperlipoproteinemia . Am J Dis Child 128:67-72, 1974;.

Howland J: Prolonged intolerance to carbohydrates . Trans Am Pediatric Soc 33:11-19, 1921;.

Davidson A: Chronic nonspecific diarrhea , in Gellis S, Kagen B (eds): Current Pediatric Therapy . Philadelphia, WB Saunders Co, 1973;, vol 6, pp 192-193.

Hunt J, Knox M: A relation between the chain length of fatty acids and the slowing of gastric emptying . J Physiol 194:327-336, 1968;.

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal