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March 1979, Vol 133, No. 3 >
Article | March 1979

Systemic Group D Streptococcal Infection in Newborn Infants

John J. Buchino, MD; Ernest Ciambarella, MD; Irwin Light, MD
Am J Dis Child. 1979;133(3):270-273. doi:10.1001/archpedi.1979.02130030046007.
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• Thirteen cases of group D streptococcal neonatal sepsis and/or meningitis were identified at the Cincinnati Children's Hospital from 1970 to 1976. Ages at onset of disease ranged from 1 to 25 days. The most frequent symptoms were fever (five cases), lethargy (five cases), and respiratory difficulty (four cases). Blood cultures for seven infants were positive; CSF cultures for five infants were positive; and CSF and blood cultures for one infant were both positive. In 12 patients, parenteral antibiotic therapy consisted of a penicillin and an aminoglycoside. One infant with a severe meningomyelocele died. The other 12 infants showed a rapid clinical response with seven patients improving within 48 hours of the start of therapy. Infection with group D streptococcus results in a low-grade systemic disease in both full-term and premature infants that responds favorably to appropriate therapy.

(Am J Dis Child 133:270-273, 1979)

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