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Simultaneous Occurrence of Extrahepatic Biliary Atresia and Fetal Alcohol Syndrome

STEPHEN L. NEWMAN, MD; DAVID B. FLANNERY, MD; DANIEL B. CAPLAN, MD
Am J Dis Child. 1979;133(1):101. doi:10.1001/archpedi.1979.02130010107027.
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Since the 1973 report by Jones and Smith1 of eight infants born to mothers who had heavy ethanol intake throughout pregnancy, the literature has been replete with articles concerning the fetal alcohol syndrome (FAS). In the human case reports and the experimental animal data previously published, there has been little mention of liver function or hepatic abnormalities. We wish to report a patient in whom FAS and extrahepatic biliary atresia (EBA) coexisted.

Report of a Case.—A 1,500-g boy was born after a 32-week gestation to a 33-year-old mother who had had three previous fullterm uncomplicated pregnancies. This last pregnancy was complicated by daily ethanol intake in which the mother consumed an average of 2 L of beer each day for the first four months of pregnancy and 750 mL of whiskey each day for the last four months. She was moderately inebriated at the time of delivery. At

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