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Mediastinal and Cervical Histoplasmosis Simulating Malignancy FREE

Charles H. Zeanah, MD; Jaime Zusman, MD
[+] Author Affiliations

Reprint requests to Department of Pediatrics, Section of Hematology-Oncology, Tulane University School of Medicine, 1430 Tulane Ave, New Orleans, LA 70112 (Dr Zusman).


Am J Dis Child. 1979;133(1):47-49. doi:10.1001/archpedi.1979.02130010053009.
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• A 12-year-old boy had a purulent mass in the anterior cervical region in association with an anterior mediastinal mass caused by Histoplasma capsulatum. The cervical mass probably represented spread of the disease, perhaps along the same pathways followed in Hodgkin's disease and other conditions that are known to involve the anterior mediastinum and the anterior cervical nodes simultaneously. An infectious disease (histoplasmosis) can cause a constellation of symptoms suggestive of a lymphoma or other malignancy.

(Am J Dis Child 133:47-49, 1979)

REFERENCES

Rusby NL:  Dermoid cysts and teratoma of mediastinum: Review .J Thorac Surg 13:169-222, 1944;.
Keefer CS:  Acute and chronic mediastinitis: Study of 60 cases . Arch Intern Med 62:109-136, 1938;.
Caplan H: Patterns of Anatomic Distribution in Hodgkin's Disease . Cambridge, Mass, Harvard University Press, 1972;, pp 196-243.
Haller JA, Mazur DO, Morgan WW Jr:  Diagnosis and management of mediastinal masses in children . J Thorac Cardiovasc Surg 58:385-393, 1969;.
Levin S:  The fungal skin test as a prognostic hindrance . J Infect Dis 122:343-344, 1970;.
Hughes WT:  Histoplasmosis capsulation and atypical Mycobacterium . Am J Dis Child 110:89, 1965;.
Goodwin RA, Nickell JA, Des Prez RM:  Mediastinal fibrosis complicating healed primary histoplasmosis and tuberculosis . Medicine 51:227-246, 1972;.
Scully RE, Galdabini JJ, McNeely BU:  Case records of the Massachusetts General Hospital: Weekly clinicopathological exercises . N Engl J Med 295:381-388, 1976;.
Zajtchuk R, Strevey TE, Heydorn WH, et al:  Mediastinal histoplasmosis: Surgical considerations . J Thorac Cardiovasc Surg 66:300-304, 1973;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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References

Rusby NL:  Dermoid cysts and teratoma of mediastinum: Review .J Thorac Surg 13:169-222, 1944;.
Keefer CS:  Acute and chronic mediastinitis: Study of 60 cases . Arch Intern Med 62:109-136, 1938;.
Caplan H: Patterns of Anatomic Distribution in Hodgkin's Disease . Cambridge, Mass, Harvard University Press, 1972;, pp 196-243.
Haller JA, Mazur DO, Morgan WW Jr:  Diagnosis and management of mediastinal masses in children . J Thorac Cardiovasc Surg 58:385-393, 1969;.
Levin S:  The fungal skin test as a prognostic hindrance . J Infect Dis 122:343-344, 1970;.
Hughes WT:  Histoplasmosis capsulation and atypical Mycobacterium . Am J Dis Child 110:89, 1965;.
Goodwin RA, Nickell JA, Des Prez RM:  Mediastinal fibrosis complicating healed primary histoplasmosis and tuberculosis . Medicine 51:227-246, 1972;.
Scully RE, Galdabini JJ, McNeely BU:  Case records of the Massachusetts General Hospital: Weekly clinicopathological exercises . N Engl J Med 295:381-388, 1976;.
Zajtchuk R, Strevey TE, Heydorn WH, et al:  Mediastinal histoplasmosis: Surgical considerations . J Thorac Cardiovasc Surg 66:300-304, 1973;.

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