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November 1978, Vol 132, No. 11 >
Article | November 1978

T3 Thyrotoxicosis FREE

MANUEL POMBO, MD; JOSE M. MARTINÓN, MD; JOSE PEÑA, MD; GERMAN STERRA, MD
Am J Dis Child. 1978;132(11):1147. doi:10.1001/archpedi.1978.02120360103024.
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Sir.—Reporting a case of T3 thyrotoxicosis in a child, Weiss et al (132:374-375, 1978) postulated that in pediatric patients the disease may be more common than indicated by the few reported cases.

We have had the opportunity to study a T3 toxicosis in a 10-year-old girl with diffuse goiter and exophthalmus. Thyroid studies showed normal serum thyroxine (T4) level, raised serum triiodothyronine (T3) level, raised uptake of radioactive iodine by thyroid, and absence of serum thyroid-stimulating hormone response to thyrotrophin-releasing hormone.1 In spite of the fact that both low or high iodide ingestion have been reported as an etiologic factor in some cases of T3 thyrotoxicosis, a detailed dietary history did not disclose data to support such an etiology in our patient. Poor iodination of thyroglobulin,2 interference in the peripherical conversion of T4 to T3,3 or the presence of thyroidstimulating

REFERENCES

1 +
Pombo M, Martinón JM, Pereira J, et al:  Toxicosis T, en una niña . Endocrinología , to be published.
2 +
Harland PC, McArthur RG, Fawcett DM:  T, toxicosis in children . Acta Paediatr Scand 66:525-528, 1977;.
3 +
Chopra IJ:  An assessment of daily production and significance of thyroidal secretion of 3,3′,5′-triiodothyronine (reverse T3) in man . J Clin Invest 58:32, 1976;.
4 +
Hall R, Besser GM:  Endocrine function , in Latner AL (ed): Cantarow and Trumper Clinical Biochemistry , ed 7. Philadelphia, WB Saunders Co, 1975;, p 766.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Pombo M, Martinón JM, Pereira J, et al:  Toxicosis T, en una niña . Endocrinología , to be published.
2 +
Harland PC, McArthur RG, Fawcett DM:  T, toxicosis in children . Acta Paediatr Scand 66:525-528, 1977;.
3 +
Chopra IJ:  An assessment of daily production and significance of thyroidal secretion of 3,3′,5′-triiodothyronine (reverse T3) in man . J Clin Invest 58:32, 1976;.
4 +
Hall R, Besser GM:  Endocrine function , in Latner AL (ed): Cantarow and Trumper Clinical Biochemistry , ed 7. Philadelphia, WB Saunders Co, 1975;, p 766.

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