Jaundice and Breast-Feeding Among Alaskan Eskimo Newborns FREE

Quentin Fisher, MD; Michael I. Cohen, MD; Linda Curda, CNM, MPH; Helen McNamara, MA

Reprint requests to Division of Adolescent Medicine, Department of Pediatrics, Montefiore Hospital and Medical Center, 111 E 210th St, Bronx, NY 10467 (Dr Cohen).

Am J Dis Child. 1978;132(9):859-861. doi:10.1001/archpedi.1978.02120340035005.

Text Size: A A A

Published online

Article

References

Comments

ABSTRACT

ABSTRACT | REFERENCES

• The course, incidence, and severity of neonatal jaundice was studied in 95 Alaskan Eskimo infants. Breast-fed infants had higher bilirubin concentrations than bottle-fed babies. Both groups experienced high bilirubin levels, similar to those previously reported in Navajo and Oriental infants but greater than those observed in whites and blacks. A marked capacity to inhibit hepatic glucuronyl transferase was observed in breast-milk specimens but only partly accounted for the bilirubin differences between breast-fed and bottle-fed Eskimo infants. These data suggest that in some racial groups predisposed to neonatal jaundice, feeding practices significantly alter the course and severity of hyperbilirubinemia.

(Am J Dis Child 114:859-861, 1978)

REFERENCES

ABSTRACT | REFERENCES

Schnier MH, Levin SE: Hyperbilirubinemia and kernicterus in premature and full-term Bantu newborn infants . Br Med J 1:1004-1007, 1959;.

Hunt AL, Moores P, Plampin DW: The incidence and severity of jaundice in the newborn in Salisbury, South Rhodesia . Cent Afr J Med 7:351-355, 1961;.

Taylor PM, Bright NH, Birchard EL, et al: The effects of race, weight loss and the time of clamping of the umbilical cord on neonatal bilirubinemia . Biol Neonate 5:299-318, 1963;.

Brown WR, Boon WH: Ethnic group differences in plasma bilirubin levels of full-term, healthy Singapore newborns . Pediatrics 36:745-751, 1965;.

Trygstad CW, McCracken CH: The pattern of physiologic jaundice in the Sioux , abstracted. Soc Pediatr Res 5:86, 1966;.

Chopra DR, Meyer HBP, Daily WJR: An unusual pattern of jaundice in the Southwest American Indian neonate . Clin Res 19:219, 1971;.

Saland J, McNamara H, Cohen MI: Navajo jaundice: A variant of neonatal hyperbilirubinemia associated with breast feeding . J Pediatr 85:271-275, 1974;.

Malloy HT, Evelyn KA: The determination of bilirubin with the photoelectric colorimeter . J Biol Chem 119:481-490, 1937;.

Black M, Billing BH: Hepatic bilirubin UDP-glucuronyl transferase activity in liver disease and Gilbert's syndrome . N Engl J Med 280:1266-1271, 1969;.

DeLeon A, Gartner LM, Arias IM: The effect of phenobarbital on hyperbilirubinemia in glucuronyl transferase deficient rats . J Lab Clin Med 70:273-278, 1967;.

Davidson LT, Merritt KK, Weech AA: Hyperbilirubinemia in the newborn . Am J Dis Child 61:958-980, 1941;.

Dahms BB, Krauss AN, Gartner LM, et al: Breast feeding and serum bilirubin values during the first four days of life . J Pediatr 83:1049-1054, 1973;.

Yeung CY, Chan A, Lee KH: Phenobarbitone prophylaxis for neonatal hyperbilirubinemia . Pediatrics 48:372-376, 1971;.

Arias IM, Gartner LM, Seifter S, et al: P rolonged neonatal unconjugated hyperbilirubinemia associated with breast feeding and a steroid, pregnane-3-(alpha), 20 (beta)-diol, in maternal milk that inhibits glucuronide formation in vitro . J Clin Invest 43:2037-2047, 1964;.

Foliot A, Ploussard JP, Housset E, et al: Breast milk jaundice: In vitro inhibition of rat liver bilirubin-uridine diphosphate glucuronyl transferase activity and Z protein-bromosulfophthalein binding by human breast milk . Pediatr Res 10:549-598, 1976;.

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal