0
Article |

Infectious Mononucleosis

JAMES A. POLLOWITZ, MD
Am J Dis Child. 1978;132(8):819. doi:10.1001/archpedi.1978.02120330091025.
Text Size: A A A
Published online

Sir.—I would like to mention an additional clinical feature of infectious mononucleosis not included by Drs Rapp and Hewetson in their comprehensive review article in the Journal (132:78-85, 1978). In 1967, Pullen et al1 first noted the high incidence (95%) of maculopapular rashes in patients with mononucleosis who received ampicillin. This observation in adult patients was corroborated in children by a retrospective multicenter study2 that showed that the characteristic exanthem developed in all 13 patients with infectious mononucleosis who received ampicillin.

Typically, the rash begins five to ten days after beginning ampicillin therapy. Macules and papules appear first on the trunk and after three to four days, the rash becomes generalized. Pruritus is freuqently present and is often severe. This exanthem usually persists for several days and sometimes resolves with desquamation.

This high incidence (693—100%) of morbiliform eruptions contrasts sharply with the natural presentation of

Topics

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();