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Kleine-Levin Syndrome Associated With Fire Setting

Pauline S. Powers, MD; Richard Gunderman, MD
Am J Dis Child. 1978;132(8):786-789. doi:10.1001/archpedi.1978.02120330058015.
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• Kleine-Levin syndrome is characterized by periodic hypersomnia associated with megaphagia and striking behavioral and psychiatric symptoms; it occurs primarily in adolescent boys. We treated a 17-year-old boy who had typical recurring somnolent episodes. His bizarre behavior included fire setting and stealing, both of which may have represented compulsions. His EEG during a sleepy episode was diffusely abnormal with generalized slowing of background activity; as he awoke and improved clinically, his EEG returned to normal. Between episodes, his EEG was normal. The relationship between Kleine-Levin syndrome and other sleep disorders is discussed. The neurochemistry and neurocircuitry that may provide the requisite substrate for this complex and fascinating neuropsychiatric disorder are briefly reviewed.

(Am J Dis Child 132:786-789, 1978)


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