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Dermatoglyphic Alterations Associated With Acute Rheumatic Fever in Children

Shyamal K. Sanyal, FAAP, FACC; Dilp P. Mukerjee, PhD; Syad H. Ahmed, MD, DCH
Am J Dis Child. 1978;132(7):692-695. doi:10.1001/archpedi.1978.02120320052012.
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• The dermatoglyphic configurations of 78 children with acute rheumatic fever were compared with those of 46 first-degree relatives and 1,310 normal subjects. Of the children with acute rheumatic fever, 75% had an ulnar deviation of the axial triradius. In about 40% of this group, the ulnar deviation was associated with a concomitant distal displacement, which resulted in a significantly higher mean maximal angle atd (P <.001) and significantly lower mean ab and td ridge counts (P <.001) relative to normal control values. The palmar dermatoglyphics of patients with acute rheumatic fever were more closely related to the configurations of first-degree relatives than to normal controls. The dermatoglyphic profiles of six patients were nearly identical to those of their first-degree relatives, all of whom had a history of acute rheumatic fever. Presence of abnormal dermatoglyphic profiles in a large proportion of children with acute rheumatic fever supports the hypothesis that certain individuals have a genetic predisposition to this disease.

(Am J Dis Child 132:692-695, 1978)

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