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Decreased Lower Esophageal Sphincter Pressure in Children With Symptoms of Gastroesophageal Reflux FREE

ARTHUR R. EULER, MD; MARVIN E. AMENT, MD
Am J Dis Child. 1978;132(5):528-529. doi:10.1001/archpedi.1978.02120300088021.
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Esophageal manometry has proved to be a valuable technique in the evaluation of adults with gastroesophageal reflux.1.2 It has also been very useful in our understanding of the underlying pathophysiology of this disease state. Esophageal manometry was performed in children with symptoms of gastroesophageal reflux to see if it would be useful in the clinical management of these patients and also to obtain insight into the pathophysiology.

Materials and Methods.—Informed consent was obtained from the parents of all children prior to the beginning of our esophageal studies. All children fasted for eight hours before the study and no sedation was used.

Esophageal manometry was done in 26 children (11 females and 15 males) whose ages ranged from 5 to 18 years. The clinical presentation in these children was as follows: 17 had vomiting, 11 had retrosternal pain, eight had dysphagia, six had weights that were below the third

REFERENCES

Carabedian M:  Use of esophageal manometry and acid perfusion in the study of gastroesophageal reflux and hiatal hernia . Surg Clin North Am 51:589-599, 1971;.
Haddad JK:  Relation of gastroesophageal reflux to yield sphincter pressure . Gastroenterology 58:175-183, 1970;.
Euler AR, Ament ME:  Value of esophageal manometric studies in the gastroesophageal reflux of infancy . Pediatrics 1:58-61, 1977;.
Euler AR, Ament ME:  Detection of gastroesophageal reflux by Tuttle test . Pediatrics 60:65-69, 1977;.
Pope CE:  Pathophysiology and diagnosis of reflux esophagitis . Gastroenterology 70:445-454, 1976;.
Ellis HF:  Gastroesphageal reflux . Surg Clin North Am 51:575-589, 1971;.
Lipshutz WH, Gaskins RD, Lukash WM, et al:  Pathogenesis of lower esophageal sphincter incompetence . N Engl J Med 289:182-184, 1973;.
Link to Article
Benz LJ, Hootkin LA, Margulies S, et al:  A comparison of clinical measurements of gastroesophageal reflux . Gastroenterology 62:1-5, 1972;.
Moroz SP, Espinozo J, Cumming WA, et al:  Lower esophageal sphincter function in children with and without gastroesophageal reflux . Gastroenterology 71:236-241, 1976;.
Johnson DG, Herbst JJ, Oliveros MA, et al:  Evaluation of gastroesophageal reflux surgery in children . Pediatrics 59:62-68 1977;.

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References

Carabedian M:  Use of esophageal manometry and acid perfusion in the study of gastroesophageal reflux and hiatal hernia . Surg Clin North Am 51:589-599, 1971;.
Haddad JK:  Relation of gastroesophageal reflux to yield sphincter pressure . Gastroenterology 58:175-183, 1970;.
Euler AR, Ament ME:  Value of esophageal manometric studies in the gastroesophageal reflux of infancy . Pediatrics 1:58-61, 1977;.
Euler AR, Ament ME:  Detection of gastroesophageal reflux by Tuttle test . Pediatrics 60:65-69, 1977;.
Pope CE:  Pathophysiology and diagnosis of reflux esophagitis . Gastroenterology 70:445-454, 1976;.
Ellis HF:  Gastroesphageal reflux . Surg Clin North Am 51:575-589, 1971;.
Lipshutz WH, Gaskins RD, Lukash WM, et al:  Pathogenesis of lower esophageal sphincter incompetence . N Engl J Med 289:182-184, 1973;.
Link to Article
Benz LJ, Hootkin LA, Margulies S, et al:  A comparison of clinical measurements of gastroesophageal reflux . Gastroenterology 62:1-5, 1972;.
Moroz SP, Espinozo J, Cumming WA, et al:  Lower esophageal sphincter function in children with and without gastroesophageal reflux . Gastroenterology 71:236-241, 1976;.
Johnson DG, Herbst JJ, Oliveros MA, et al:  Evaluation of gastroesophageal reflux surgery in children . Pediatrics 59:62-68 1977;.

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