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Decreased Lower Esophageal Sphincter Pressure in Children With Symptoms of Gastroesophageal Reflux

Am J Dis Child. 1978;132(5):528-529. doi:10.1001/archpedi.1978.02120300088021.
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Esophageal manometry has proved to be a valuable technique in the evaluation of adults with gastroesophageal reflux.1.2 It has also been very useful in our understanding of the underlying pathophysiology of this disease state. Esophageal manometry was performed in children with symptoms of gastroesophageal reflux to see if it would be useful in the clinical management of these patients and also to obtain insight into the pathophysiology.

Materials and Methods.—Informed consent was obtained from the parents of all children prior to the beginning of our esophageal studies. All children fasted for eight hours before the study and no sedation was used.

Esophageal manometry was done in 26 children (11 females and 15 males) whose ages ranged from 5 to 18 years. The clinical presentation in these children was as follows: 17 had vomiting, 11 had retrosternal pain, eight had dysphagia, six had weights that were below the third


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