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April 1978, Vol 132, No. 4 >
Article | April 1978

Haemophilus influenzae Type b Infections FREE

NATHANIEL WYCLIFFE, MD; JULIUS LANDWIRTH, MD
Am J Dis Child. 1978;132(4):431. doi:10.1001/archpedi.1978.02120290103024.
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Sir.—The current interest in the literature1-4 in the spread of Haemophilus type b infections prompted us to add our recent experience with this problem that tends to confirm previous observations.

Three infants, ages of 10 and 17 months, were admitted within an eight-day period with serious Haemophilus influenzae type b infections, two with bacterial meningitis and one with cellulitis of the cheek (cases 1, 2, 3, Table).

The three infants were among five children younger than 2 years of age cared for during the day, as a group, in a small apartment by one grandmother babysitter. This striking coincidence of disease prompted an epidemiological investigation of immediate contacts including history, physical examination, nasopharyngeal cultures, and paired serum determinations for capsular antibody titers by radioimmunoassay technique. A total of 17 individuals were studied. The positive findings are shown in the accompanying Table.

It was noted that one of the

REFERENCES

1 +
Tejani A, Bohdan D, Nangia BS, et al:  Intrafamily spread of Haemophilus type b infection . Am J Dis Child 131:778-781, 1977;.
2 +
Ginsburg CM, McCracken GH Jr, Rae S, et al:  Haemophilus influenzae type b disease: Incidence in a day care center . JAMA 238:604-607, 1977;.
Link to Article
3 +
Melish ME, Nelson AJ, Martin TE, et al:  Epidemic spread of H influenzae type b (HIB) in a day care center . Pediatr Res 10:348, 1976;.
4 +
Glode MP, Schiffer MS, Robbins JB, et al:  An outbreak of Hemophilus influenzae type b meningitis in an enclosed hospital population . J Pediatr 88:36-40, 1976;.
Link to Article
5 +
Norden CW, Michaels RH, Melish M:  Serologic responses of children with meningitis due to Haemophilus influenzae type b . J Infect Dis 134:495-499, 1976;.
Link to Article
6 +
Smith DH, Peter G, Ingram DL, Harding AL, et al:  Responses of children immunized with the capsular polysaccharide of Hemophilus influenzae type b . Pediatrics 52:637-644, 1973;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Tejani A, Bohdan D, Nangia BS, et al:  Intrafamily spread of Haemophilus type b infection . Am J Dis Child 131:778-781, 1977;.
2 +
Ginsburg CM, McCracken GH Jr, Rae S, et al:  Haemophilus influenzae type b disease: Incidence in a day care center . JAMA 238:604-607, 1977;.
Link to Article
3 +
Melish ME, Nelson AJ, Martin TE, et al:  Epidemic spread of H influenzae type b (HIB) in a day care center . Pediatr Res 10:348, 1976;.
4 +
Glode MP, Schiffer MS, Robbins JB, et al:  An outbreak of Hemophilus influenzae type b meningitis in an enclosed hospital population . J Pediatr 88:36-40, 1976;.
Link to Article
5 +
Norden CW, Michaels RH, Melish M:  Serologic responses of children with meningitis due to Haemophilus influenzae type b . J Infect Dis 134:495-499, 1976;.
Link to Article
6 +
Smith DH, Peter G, Ingram DL, Harding AL, et al:  Responses of children immunized with the capsular polysaccharide of Hemophilus influenzae type b . Pediatrics 52:637-644, 1973;.

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