We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

'Pena-Shokeir Syndrome' in a Newborn Male Infant

Am J Dis Child. 1977;131(12):1419-1420. doi:10.1001/archpedi.1977.02120250101035.
Text Size: A A A
Published online

Two sisters1 and two unrelated male infants2 were reported to have a rare syndrome of camptodactyly, ankylosis, facial anomalies, and pulmonary hypoplasia. Camptodactyly is herein defined as permanent flexion of one or more fingers, and ankylosis as an immobility and consolidation of joints. We report an additional similar case of an infant who was initially suspected of having trisomy 18 syndrome, but who was subsequently found to possess those characteristics of the "Pena-Shokeir syndrome." Although this case could be classified as arthrogryposis multiplex congenita,3 a more descriptive diagnosis that may elucidate the etiology and enhance the treatment of this disorder is desired.

Report of a Case.—A male infant weighing 1,000 gm was born to a 23-year-old gravida 3, para 3, abortus 0 mother after 36½ weeks of gestation. The father was 25 years old. The mother reported nausea and vomiting during the third month. Neither parent


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.