0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Acute Granulocytic Leukemia Following Successful Treatment of Rhabdomyosarcoma

MICHAEL F. HENSLEY, DO; AYTEN CANGIR, MD; STEVEN J. CULBERT, MD; JAN VAN EYS, MD, PHD
Am J Dis Child. 1977;131(12):1417. doi:10.1001/archpedi.1977.02120250099032.
Text Size: A A A
Published online

The occurence of second malignant neoplasms in young patients whose primary neoplasm had been controlled is being observed more frequently as survival time increases. The second malignant neoplasms may be due to genetic factors, treatment, or an interaction of both.

A recent study of 414 long-term survivors of childhood cancer estimated the 20-year cumulative probability of a second cancer in patients receiving radiation to be 17%.1 There is also evidence for the occurrence of second malignant neoplasms in patients who have received chemotherapeutic agents.2

We report the case of a patient previously treated for alveolar rhabdomyosarcoma with radiotherapy and multiple chemotherapeutic agents in whom acute granulocytic leukemia (AGL) developed.

Report of a Case.—In March 1973, this 3½-year-old girl complained of right forearm pain and subsequently developed a palpable axillary lymph node. A biopsy specimen of the right forearm and axillary node revealed alveolar rhabdomyosarcoma. The patient received

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();