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Renal Failure as a Presenting Sign of Diffuse Sarcoidosis in an Adolescent Girl FREE

Miriam C. Turner, MD; Moon L. Shin, MD; Edward J. Ruley, MD
[+] Author Affiliations

Reprint requests to Department of Pediatrics, University of Maryland Hospital, Howard Hall Tower I, Room 10-047, Baltimore, MD 21201 (Dr Ruley).


Am J Dis Child. 1977;131(9):997. doi:10.1001/archpedi.1977.02120220063010.
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• We report a renal failure due to sarcoid granulomatous infiltration of the kidney that was documented by renal biopsy in an adolescent black albino girl. Treatment with prednisone was associated with improvement in the clinical disease and the histologic picture on repeat biopsy. With cessation of prednisone there was clinical and histological relapse while reinstitution of prednisone therapy was again associated with improvement. Experience with this child, as well as that reported previously in seven similar adult patients, would indicate that prednisone is an effective drug to control this unusual problem.

(Am J Dis Child 131:997-1000, 1977)

REFERENCES

Coburn JW, Hobbs C, Johnston GS, et al:  Granulomatous sarcoid nephritis . Am J Med 42:273-282, 1967;.
Link to Article
Kogurt MD, Neumann LL:  Renal involvement in Boeok's sarcoidosis . Pediatrics 28:410-424, 1961;.
Falls WF, Randall RE, Sommers SC, et al:  Nonhypercalcemic sarcoid nephropathy . Arch Intern Med 130:285-291, 1972;.
Link to Article
Berger KW, Relman AS:  Renal impairment due to sarcoid infiltration of the kidney . N Engl J Med 252:44-49, 1955;.
Link to Article
Ogilvie RI, Kaye M, Moore S:  Granulomatous sarcoid disease of the kidney . Ann Intern Med 61:711-715, 1964;.
Link to Article
Panitz F, Shinaberger JH:  Nephrogenic diabetes insipidus due to sarcoidosis without hypercalcemia . Ann Intern Med 62:113-119, 1965;.
Link to Article
Bourke E, Barniville H:  Granulomatous sarcoid nephritis . Ir J Med Sci 142:127-131, 1973;.
Link to Article
Bolton WK, Atuk NO, Rametta C, et al:  Isolated renal sarcoidosis . Abstr Am Soc Nephrol 1974;, p 11.
Shiff AD, Blatt C, Colp C:  Recurrent effusion secondary to pericardial sarcoid . N Engl J Med 281:141-143, 1969;.
Link to Article
McCoy RC, Tissher CC:  Glomerulonephritis associated with sarcoidosis . Am J Pathol 68:339-358, 1972;.
Grupe WE, Kaplan MH:  Demonstration of an antibody to proximal tubular antigen in the pathogenesis of experimental autoimmune nephrosis in rats . J Lab Clin Med 74:400-409, 1969;.
Dinh BL, Brassard A, Katiyar VN:  Experimental glomerulonephritis induced with the major antigen of rat kidney . Int Arch Allergy Appl Immunol 43:131-143, 1972;.
Link to Article
Edington TS, Glassock RJ, Dixon FJ:  Autologous immune complex nephritis induced with renal tubular antigen, part 1 . J Exp Med 127:555-571, 1968;.
Link to Article
Glassock RJ, Edington TS, Watson TI, et al:  Autologous immune complex nephritis induced with renal tubular antigen, part 2 . J Exp Med 127:573-587, 1968;.
Link to Article
Strauss J, Pardo V, Kramer H, et al:  Sickle cell nephropathy and autologous immune complex nephritis . Abstr Am Soc Nephrol , 1973;, p 101.

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References

Coburn JW, Hobbs C, Johnston GS, et al:  Granulomatous sarcoid nephritis . Am J Med 42:273-282, 1967;.
Link to Article
Kogurt MD, Neumann LL:  Renal involvement in Boeok's sarcoidosis . Pediatrics 28:410-424, 1961;.
Falls WF, Randall RE, Sommers SC, et al:  Nonhypercalcemic sarcoid nephropathy . Arch Intern Med 130:285-291, 1972;.
Link to Article
Berger KW, Relman AS:  Renal impairment due to sarcoid infiltration of the kidney . N Engl J Med 252:44-49, 1955;.
Link to Article
Ogilvie RI, Kaye M, Moore S:  Granulomatous sarcoid disease of the kidney . Ann Intern Med 61:711-715, 1964;.
Link to Article
Panitz F, Shinaberger JH:  Nephrogenic diabetes insipidus due to sarcoidosis without hypercalcemia . Ann Intern Med 62:113-119, 1965;.
Link to Article
Bourke E, Barniville H:  Granulomatous sarcoid nephritis . Ir J Med Sci 142:127-131, 1973;.
Link to Article
Bolton WK, Atuk NO, Rametta C, et al:  Isolated renal sarcoidosis . Abstr Am Soc Nephrol 1974;, p 11.
Shiff AD, Blatt C, Colp C:  Recurrent effusion secondary to pericardial sarcoid . N Engl J Med 281:141-143, 1969;.
Link to Article
McCoy RC, Tissher CC:  Glomerulonephritis associated with sarcoidosis . Am J Pathol 68:339-358, 1972;.
Grupe WE, Kaplan MH:  Demonstration of an antibody to proximal tubular antigen in the pathogenesis of experimental autoimmune nephrosis in rats . J Lab Clin Med 74:400-409, 1969;.
Dinh BL, Brassard A, Katiyar VN:  Experimental glomerulonephritis induced with the major antigen of rat kidney . Int Arch Allergy Appl Immunol 43:131-143, 1972;.
Link to Article
Edington TS, Glassock RJ, Dixon FJ:  Autologous immune complex nephritis induced with renal tubular antigen, part 1 . J Exp Med 127:555-571, 1968;.
Link to Article
Glassock RJ, Edington TS, Watson TI, et al:  Autologous immune complex nephritis induced with renal tubular antigen, part 2 . J Exp Med 127:573-587, 1968;.
Link to Article
Strauss J, Pardo V, Kramer H, et al:  Sickle cell nephropathy and autologous immune complex nephritis . Abstr Am Soc Nephrol , 1973;, p 101.

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