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Article |

Prune-Belly Syndrome Associated With Potter (Renal Nonfunction) Syndrome

Arun K. Pramanik, MD; Geoffrey Altshuler, MB, BS; Irwin J. Light, MD; James M. Sutherland, MD
Am J Dis Child. 1977;131(6):672-674. doi:10.1001/archpedi.1977.02120190066013.
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• Three fatal cases of prune-belly syndrome were associated with nonrenal features of Potter syndrome. The abdominal muscle hypoplasia is thought to be a result of large kidneys compressing the developing abdominal musculature during a critical phase of fetal development. Thus, Potter syndrome and prune-belly syndrome may coexist when nonfunctioning large kidneys result in oligohydramnios. A teratogenic role of cytomegalovirus inclusion disease and other viruses is possible in the pathogenesis of these syndromes.

(Am J Dis Child 131:672-674, 1977)


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