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Article |

Echocardiography in Cystic Fibrosis

Michael Gewitz, MD; Eshagh Eshaghpour, MD; Douglas S. Holsclaw, MD; Howard A. Miller, MD; Nobuyoshi Kawai, MD
Am J Dis Child. 1977;131(3):275-280. doi:10.1001/archpedi.1977.02120160029003.
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• Echocardiograms were obtained for 25 patients with cystic fibrosis (CF) and 20 controls to evaluate this technique as a means of assessment of right ventricular changes in patients with CF. Right ventricular anterior wall thickness per square meter of body surface (RVAW/sq m) and right ventricular internal dimension per square meter of body surface (RVID/sq m) were compared with other techniques for detection of cor pulmonale. Significant correlations existed between both RVAW/sq m and RVID/sq m and the forced vital capacity, forced expiratory volume in one second, midmaximal expiratory flow rate, clinical score of severity of disease, and roentgenographic score of pulmonary involvement. The RVAW/sq m was slightly more sensitive than RVID/sq m; RVAW/sq m thickness on echocardiogram in vivo compared well with actual measurements at autopsy in five patients. No correlations were found between echocardiography and electrocardiograms, vectorcardiograms, thoracic index, or cardiothoracic ratio.

(Am J Dis Child 131:275-280, 1977)


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