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Radionuclide Imaging of Airway Obstruction Following Assisted Ventilation FREE

Gary F. Gates, MD; Earl K. Dore, MD; Marguerite Markarian, MD; Jean Takanaka, MD
[+] Author Affiliations

Reprint requests to Department of Radiology, Children's Hospital of Los Angeles, 4650 Sunset Blvd, PO Box 54700, Los Angeles, CA 90054 (Dr Gates).


Am J Dis Child. 1976;130(11):1222-1227. doi:10.1001/archpedi.1976.02120120056009.
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• Radioaerosol lung scintigraphy was performed in five infants in whom obstructive airway complications developed following assisted ventilation. These studies suggest that a primary functional defect was obstruction to airflow at the level of the major airways, which occurred during expiration. Perfusion lung scintigraphy showed areas of diminished or redistributed pulmonary blood flow, which, like the results of the radioaerosol scintigraphic studies, are findings often associated with adult chronic obstructive pulmonary disease.

(Am J Dis Child 130:1222:1227, 1976)

REFERENCES

Northway WH Jr, Rosan RC, Porter DY:  Pulmonary disease following respirator therapy of hyaline-membrane disease: Bronchopulmonary dysplasia . N Engl J Med 276:357-368, 1967;.
Northway WH Jr, Rosan RC:  Radiographic features of pulmonary oxygen toxicity in the newborn: Bronchopulmonary dysplasia . Radiology 91:49-58, 1968;.
Rowland R, Newman CGH:  Pulmonary complications of oxygen therapy . J Clin Pathol 22:192-198, 1969;.
Weisser K, Ganz R, Olafsson A, et al:  Bronchopulmonary dysplasia in the premature baby . Respiration 27( (suppl) ):36-40, 1970;.
Tsai SH, Anderson WR, Strickland MB, et al:  Bronchopulmonary dysplasia associated with oxygen therapy in infants with respiratory distress syndrome . Radiology 105:107-112, 1972;.
Auld PAM:  Oxygen therapy for premature infants . J Pediatr 78:705-709, 1971;.
Shepard FM, Johnston RB Jr, Klatte EC, et al:  Residual pulmonary findings in clinical hyaline-membrane disease . N Engl J Med 279:1063-1071, 1968;.
Stern L, Ramos AD, Outerbridge EW, et al:  Negative pressure artificial respiration: Use in treatment of respiratory failure of the newborn . Can Med Assoc J 102:595-601, 1970;.
Stern L:  The use and misuse of oxygen in the newborn infant . Pediatr Clin North Am 20:447-464, 1973;.
Berg TJ, Pagtakhan RD, Reed MH, et al:  Bronchopulmonary dysplasia and lung rupture in hyaline membrane disease: Influence of continuous distending pressure . Pediatrics 55:51-54, 1975;.
Banerjee CK, Girling DJ, Wigglesworth JS:  Pulmonary fibroplasia in newborn babies treated with oxygen and artificial ventilation . Arch Dis Child 47:509-518, 1972;.
Philip AGS:  Oxygen plus pressure plus time: The etiology of bronchopulmonary dysplasia . Pediatrics 55:44-50, 1975;.
Burrows FGO, Edwards JM:  A pulmonary disease in patients ventilated with high oxygen concentrations . Br J Radiol 43:848-855, 1970;.
Westgate HD, Fisch RO, Langer LO, et al:  Pulmonary and respiratory function changes in survivors of hyaline-membrane disease . Dis Chest 55:465-470, 1969;.
Pusey VA, MacPherson RI, Chernick V:  Pulmonary fibroplasia following prolonged artificial ventilation of newborn infants . Can Med Assoc J 100:451-457, 1969;.
Thibeault DW, Hagstrom JWC, Auld PA:  Radiologic findings in the lungs of premature infants . J Pediatr 74:1-10, 1969;.
Wang AH, Naiman JL, Kendall N, et al:  Wilson-Mikity syndrome followed by "idiopathic" pulmonary hemosiderosis . J Pediatr 78:503-506, 1971;.
McSweeney WJ:  Radiologic evaluation of the newborn with respiratory distress . Semin Roentgenol 7:65-83, 1972;.
Wesenberg RL:  Complications of mechanically assisted ventilation: Respirator lung disease, bronchopulmonary dysplasia , in The Newborn Chest . Hagerstown, Md, Harper & Row Publishers Inc, 1973;, pp 135-147.
Dore EK, Poe ND, Ellestad MH, et al:  Lung perfusion and inhalation scanning in pulmonary emphysema . Am J Roentgenol Radium Ther Nucl Med 104:770-776, 1968;.
Taplin GV:  Scintiscanning in the assessment of regional pulmonary function , in Gordon BL (ed): Clinical Cardiopulmonary Physiology , ed 3. New York, Grune & Stratton Inc, 1969;, pp 437-464.
Taplin GV, Poe ND:  Pulmonary function and disease: Radioaerosol inhalation scanning , in Blahd WH (ed): Nuclear Medicine , ed 2. New York, McGraw-Hill Book Co Inc, 1971;, pp 336-341.
Fraser RG, Macklem PT, Brown WG:  Airway dynamics in bronchiectasis: A combined cinefluorographic-manometric study . Am J Roentgenol Radium Ther Nucl Med 93:821-835, 1965;.
Wittenborg MH, Gyepes MT, Crocker D:  Tracheal dynamics in infants with respiratory distress, stridor, and collapsing trachea . Radiology 88:653-662, 1967;.
Lourenco RV, Loddenkemper R, Carton RW:  Patterns of distribution and clearance of aerosols in patients with bronchiectasis . Am Rev Respir Dis 106:857-866, 1972;.

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References

Northway WH Jr, Rosan RC, Porter DY:  Pulmonary disease following respirator therapy of hyaline-membrane disease: Bronchopulmonary dysplasia . N Engl J Med 276:357-368, 1967;.
Northway WH Jr, Rosan RC:  Radiographic features of pulmonary oxygen toxicity in the newborn: Bronchopulmonary dysplasia . Radiology 91:49-58, 1968;.
Rowland R, Newman CGH:  Pulmonary complications of oxygen therapy . J Clin Pathol 22:192-198, 1969;.
Weisser K, Ganz R, Olafsson A, et al:  Bronchopulmonary dysplasia in the premature baby . Respiration 27( (suppl) ):36-40, 1970;.
Tsai SH, Anderson WR, Strickland MB, et al:  Bronchopulmonary dysplasia associated with oxygen therapy in infants with respiratory distress syndrome . Radiology 105:107-112, 1972;.
Auld PAM:  Oxygen therapy for premature infants . J Pediatr 78:705-709, 1971;.
Shepard FM, Johnston RB Jr, Klatte EC, et al:  Residual pulmonary findings in clinical hyaline-membrane disease . N Engl J Med 279:1063-1071, 1968;.
Stern L, Ramos AD, Outerbridge EW, et al:  Negative pressure artificial respiration: Use in treatment of respiratory failure of the newborn . Can Med Assoc J 102:595-601, 1970;.
Stern L:  The use and misuse of oxygen in the newborn infant . Pediatr Clin North Am 20:447-464, 1973;.
Berg TJ, Pagtakhan RD, Reed MH, et al:  Bronchopulmonary dysplasia and lung rupture in hyaline membrane disease: Influence of continuous distending pressure . Pediatrics 55:51-54, 1975;.
Banerjee CK, Girling DJ, Wigglesworth JS:  Pulmonary fibroplasia in newborn babies treated with oxygen and artificial ventilation . Arch Dis Child 47:509-518, 1972;.
Philip AGS:  Oxygen plus pressure plus time: The etiology of bronchopulmonary dysplasia . Pediatrics 55:44-50, 1975;.
Burrows FGO, Edwards JM:  A pulmonary disease in patients ventilated with high oxygen concentrations . Br J Radiol 43:848-855, 1970;.
Westgate HD, Fisch RO, Langer LO, et al:  Pulmonary and respiratory function changes in survivors of hyaline-membrane disease . Dis Chest 55:465-470, 1969;.
Pusey VA, MacPherson RI, Chernick V:  Pulmonary fibroplasia following prolonged artificial ventilation of newborn infants . Can Med Assoc J 100:451-457, 1969;.
Thibeault DW, Hagstrom JWC, Auld PA:  Radiologic findings in the lungs of premature infants . J Pediatr 74:1-10, 1969;.
Wang AH, Naiman JL, Kendall N, et al:  Wilson-Mikity syndrome followed by "idiopathic" pulmonary hemosiderosis . J Pediatr 78:503-506, 1971;.
McSweeney WJ:  Radiologic evaluation of the newborn with respiratory distress . Semin Roentgenol 7:65-83, 1972;.
Wesenberg RL:  Complications of mechanically assisted ventilation: Respirator lung disease, bronchopulmonary dysplasia , in The Newborn Chest . Hagerstown, Md, Harper & Row Publishers Inc, 1973;, pp 135-147.
Dore EK, Poe ND, Ellestad MH, et al:  Lung perfusion and inhalation scanning in pulmonary emphysema . Am J Roentgenol Radium Ther Nucl Med 104:770-776, 1968;.
Taplin GV:  Scintiscanning in the assessment of regional pulmonary function , in Gordon BL (ed): Clinical Cardiopulmonary Physiology , ed 3. New York, Grune & Stratton Inc, 1969;, pp 437-464.
Taplin GV, Poe ND:  Pulmonary function and disease: Radioaerosol inhalation scanning , in Blahd WH (ed): Nuclear Medicine , ed 2. New York, McGraw-Hill Book Co Inc, 1971;, pp 336-341.
Fraser RG, Macklem PT, Brown WG:  Airway dynamics in bronchiectasis: A combined cinefluorographic-manometric study . Am J Roentgenol Radium Ther Nucl Med 93:821-835, 1965;.
Wittenborg MH, Gyepes MT, Crocker D:  Tracheal dynamics in infants with respiratory distress, stridor, and collapsing trachea . Radiology 88:653-662, 1967;.
Lourenco RV, Loddenkemper R, Carton RW:  Patterns of distribution and clearance of aerosols in patients with bronchiectasis . Am Rev Respir Dis 106:857-866, 1972;.

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