0
December 1974, Vol 128, No. 6 >
Article | December 1974

Hyperglycemia Without Ketosis or Hypernatremia FREE

KATHALEEN C. PERKINS, MD
Am J Dis Child. 1974;128(6):885. doi:10.1001/archpedi.1974.02110310133025.
Text Size: A A A
Published online
Article
References
Comments

In hyperosmolar dehydration due to enteric disease, hyperglycemia may occur with or without elevation of the serum acetone level or sodium level or both.1 The following case reemphasizes the importance of recognizing this transient abnormality and of treatment by hydration alone. The use of insulin is contraindicated.2

Report of a Case.—An 11-month-old, prematurely born twin boy was hospitalized following one week of fever and gastroenteritis. He had continued taking skim milk and baby food. Family history of diabetes was denied.

Physical examination showed a temperature of 40.6 C (105.1 F); pulse rate, 160 beats per minute; respiration rate, 40/minute; weight, 6.07 kg (13.4 lb) (1.5-kg [3.3-lb] loss in three weeks). He was listless and cyanotic, and he had a weak, ineffectual cough. Skin turgor was poor, eyes were sunken, and rhonchi were heard at the left lung base.

Attempts at intravenous hydration were largely unsuccessful, and during

REFERENCES

1 +
Stevenson RE, Bowyer FP:  Hyperglycemia with hyperosmolar dehydration in nondiabetic infants . J Pediatr 77:818-823, 1970;.
2 +
Finberg L:  Hypernatremic (hypertonic) dehydration in infants . N Engl J Med 289:196-198, 1974;.
3 +
White A, Handler P, Smith EL: Principles of Biochemistry , ed 5. New York, McGraw-Hill Book Co Inc, 1973;, pp 412-513 and 1072-1104.
4 +
Loggie JMH, Van Maanen EF:  The autonomic nervous system and some aspects of the use of autonomic drugs in children: I . J Pediatr 81:205-216, 1972;.
5 +
Arieff AL, Kleeman CR:  Studies on the mechanisms of cerebral edema in diabetic comas: Effects of hyperglycemia and rapid lowering of plasma glucose in normal rabbits . J Clin Invest 52:571-583, 1973;.
6 +
Young E, Bradley RF:  Cerebral edema with irreversible coma in severe diabetic ketoacidosis . N Engl J Med 276:665-669, 1967;.

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Stevenson RE, Bowyer FP:  Hyperglycemia with hyperosmolar dehydration in nondiabetic infants . J Pediatr 77:818-823, 1970;.
2 +
Finberg L:  Hypernatremic (hypertonic) dehydration in infants . N Engl J Med 289:196-198, 1974;.
3 +
White A, Handler P, Smith EL: Principles of Biochemistry , ed 5. New York, McGraw-Hill Book Co Inc, 1973;, pp 412-513 and 1072-1104.
4 +
Loggie JMH, Van Maanen EF:  The autonomic nervous system and some aspects of the use of autonomic drugs in children: I . J Pediatr 81:205-216, 1972;.
5 +
Arieff AL, Kleeman CR:  Studies on the mechanisms of cerebral edema in diabetic comas: Effects of hyperglycemia and rapid lowering of plasma glucose in normal rabbits . J Clin Invest 52:571-583, 1973;.
6 +
Young E, Bradley RF:  Cerebral edema with irreversible coma in severe diabetic ketoacidosis . N Engl J Med 276:665-669, 1967;.

Correspondence

Submit a Letter
CME
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Clear Answers | Save For Later
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Compression-Only CPR: Pushing the Science Forward
Cone
AAM 2010;304:1493-1495.
All you need to read in the other general journals
BMJ 2010;341:c5893-c1494.
Submit a Comment

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

© 2013 American Medical Association. All Rights Reserved.
Powered bySilverchair Information Systems