To the Editor.—The report of J. Leonidas et al in the December issue of the Journal (126:806-808, 1973) of the association of Ménétrier disease and cytomegalovirus infection was of interest to me. I have also seen such a patient. The accompanying figure demonstrates the typical inclusion body in the gastric mucosa of this patient, who also had the hypoprote
Section of gastric mucosa showing inclusion body (hematoxylin-eosin, original magnification × 500). inemia and edema that is characteristic of this disease. Unfortunately, virus titers could not be done. It is possible that the alterations in the gastric mucosa in Ménétrier disease increase the chance of cytomegalovirus infection.