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Silver-Russell Dwarfism and Cystic Fibrosis

Am J Dis Child. 1974;127(5):760-761. doi:10.1001/archpedi.1974.02110240146027.
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To the Editor.—In the April issue of the Journal (125:495-503, 1973), Taussig et al reported a case of a 6-year-old boy with the Russell variant of the Silver-Russell syndrome concomitant with cystic fibrosis. We would like to describe another patient who had the same combination of diseases.

Report of a Case  A girl, now 7 years old, was born to healthy parents after an uneventful 37 to 38 weeks' gestation. At birth, she weighed 2,250 gm (4.9 lb) and her length was 48 cm (18.9 in). The placenta was small. The delivery was uncomplicated and the neonatal course was normal. The parents and two half-brothers are of normal height. A grandmother was of short stature and had an appearance somewhat similar to that of our patient, but, otherwise, she was normal.The baby showed failure to thrive; she had feeding difficulties, retarded growth, and poor weight gain. Her stools were


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