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Placental Transfusion

Alice C. Yao, MD; John Lind, MD
Am J Dis Child. 1974;127(1):128-141. doi:10.1001/archpedi.1974.02110200130021.
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Mechanism  The blood volume (BV) of the newborn term infant varies over a wide range depending on the amount of placental transfusion at birth. Indirectly, placental transfusion has been shown by an increase of 55 gm to as much as 180 gm in weight of the infant during the first minutes of life when the umbilical cord was left unclamped. The amount of blood involved was estimated to be more than 40% of the infant's BV when cords were clamped immediately.1 Direct measurement of the infant's BV, which also takes into account the transfer of blood from the placenta to the infant during the first two stages of delivery, varied from 55 to 150 ml/kg.2,3 When cord clamping was delayed for three to five minutes ("late-clamped") and BV determined 8 to 15 minutes after birth, there was an increment of 33% compared to that of infants whose cords


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