Article |

Cytomegalovirus Infection and Toxoplasma

Am J Dis Child. 1973;126(6):860-861. doi:10.1001/archpedi.1973.02110190702029.
Text Size: A A A
Published online


To the Editor.—I reviewed sections from the lung of the stillborn baby with cytomegalovirus infection (CMV), the report of which was published by Demian et al in the Journal (125:420-421, 1973). The authors kindly drew circles around more than 11 cells containing supposed double infections involving CMV and Toxoplasma. However, in my opinion, all the cytoplasmic inclusions are those of CMV. This report, and others (JAMA 198:203, 1966) indicate that intranuclear inclusions of CMV are recognized, but that cytoplasmic inclusions are sometimes misinterpreted as Toxoplasma. Numerous publications have recognized both types of inclusions, and the viral nature of the cytoplasmic inclusions is confirmed by ultrastructural studies, such as that by McGavin and Smith (Exp Mol Pathol 4:1-10, 1965) and Luna and Lichtiger (Am J Clin Pathol 55:499-505, 1971). Double infections of cultured cells have been produced experimentally (Nature 220:299-300, 1968; Science 160:1130-1132, 1968). In the latter publication, the difference


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview





Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.