Ménétrier Disease and Cytomegalovirus Infection in Childhood FREE

John C. Leonidas, MD; Eugene C. Beatty, MD; Herbert A. Wenner, MD

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Received for publication May 21, 1973; accepted July 2.

Reprint requests to Children's Mercy Hospital, 24th at Gillham Road, Kansas City, MO 64108 (Dr. Leonidas).

Am J Dis Child. 1973;126(6):806-808. doi:10.1001/archpedi.1973.02110190648013.

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ABSTRACT

ABSTRACT | REFERENCES

Cytomegalic inclusions, characteristic of infection with cytomegalovirus, were found in the hypertrophic gastric mucosa of a 3½-year-old child with giant hypertrophic gastritis and protein loss in the gastrointestinal tract (Ménétrier disease). There was a tardy 16-fold rise of complement fixation titers against cytomegalovirus soon after the acute phase of the illness. To our knowledge, the association of Ménétrier disease and cytomegalovirus has been reported only once before.

REFERENCES

ABSTRACT | REFERENCES

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Sandberg DH: Hypertrophic gastropathy (Ménétrier's disease) in childhood . J Pediatr 78:866-868, 1971;.
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Citrin Y, Sterling K, Halsted JA: The mechanism of hypoproteinemia associated with giant hypertrophy of the gastric mucosa . N Engl J Med 257:906-912, 1957;.
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Reese DF, Hodgson JR, Dockerty MB: Giant hypertrophy of the gastric mucosa (Ménétrier's disease): A correlation of the roentgenographic, pathologic and clinical findings . Am J Roentgenol Radium Ther Nucl Med 88:619-626, 1962;.

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Herskovic T, Spiro HM, Gryboski JD: Acute transient gastrointestinal protein loss . Pediatrics 41:818-821, 1968;.

Jarnum S, Jensen KB: Plasma protein turnover (albumin, transferin, IgG, IgM) in Ménétrier's disease (giant hypertrophic gastritis): Evidence for nonselective protein loss . Gut 13:128-137, 1972;.
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Levine RS, Warner NE, Johnson CF: Cytomegalic inclusion disease in the gastrointestinal tract of adults . Ann Surg 159:37-48, 1964;.
Link to Article

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