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Microbiologic Studies on Young Infants With Lower Respiratory Tract Disease

Lowell M. Zollar, MD, MPH; Helen E. Krause, RN; Maurice A. Mufson, MD
Am J Dis Child. 1973;126(1):56-60. doi:10.1001/archpedi.1973.02110190052010.
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Viral infections account for most lower respiratory tract infections in young infants (less than 60 days of age). Respiratory syncytial and parainfluenza 3 virus infections accounted for approximately three fourths of the identified virus infections. Other agents were isolated infrequently.

Overall, viruses were recovered from 21% of the infants with pneumonia and 25% of the infants with bronchiolitis. Sixteen (18.0%) of 89 infants from whom paired sera were collected had diagnostic antibody rises. Four of five infants with bacteremia also had virus infections. Viral infections of the respiratory tract may play a role in the dissemination of bacterial disease.


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