0
May 1973, Vol 125, No. 5 >
Article | May 1973

Nephrosis, Steroids, Pancreatitis, and Diabetic Ketoacidosis FREE

Akio Kobayashi, MD; Takeko Utsunomiya, MD; Masako Horino, MD; Yoshiro Ohbe, MD; Junichi Hata, MD
[+] Author Affiliations

Received for publication Feb 4, 1972; accepted Dec 29.

Reprint requests to the Department of Pediatrics, National Children's Hospital, Taishido 3-35-31, Setagaya-ku, Tokyo (Dr. Kobayashi).


Am J Dis Child. 1973;125(5):726-729. doi:10.1001/archpedi.1973.04160050072015.
Text Size: A A A
Published online
Article
References
Comments

A boy, age 97/12 years, developed diabetic ketoacidosis with acute hemorrhagic pancreatitis during long-term corticosteroid and short-term cyclophosphamide therapy for steroid-dependent nephrosis.

REFERENCES

1 +
Lazarus SS, Bencosme SA:  Alterations of pancreas during cortisone diabetes in rabbits . Proc Soc Exp Biol Med 89:114-118, 1955;.
2 +
Stumpf HH, Wilens SL, Somoza C:  Pancreatic lesions and peripancreatic fat necrosis in cortisonetreated rabbits . Lab Invest 5:224-235, 1956;.
3 +
Carone FA, Liebow AA:  Acute pancreatic lesions in patients treated with Acth and adrenal corticoids . New Engl J Med 257:690-697, 1957;.
4 +
Baar HS, Wolff OH:  Pancreatic necrosis in cortisone-treated children . Lancet 1:812-815, 1957;.
5 +
Marczynska-Robowska M:  Pancreatic necrosis in a case of Still's disease . Lancet 1:815-816, 1957;.
6 +
Bourne MS, Dawson H:  Acute pancreatitis complicating prednisolone therapy . Lancet 2:1209-1210, 1958;.
7 +
Oppenheimer EH, Boitnott JK:  Pancreatitis in children following adrenal cortico-steroid therapy . Bull Hopkins Hosp 107:297-306, 1960;.
8 +
Nelp WB:  Acute pancreatitis associated with steroid therapy . Arch Intern Med 108:102-110, 1961;.
9 +
Riemenschneider TA, Wilson JF, Vernier RL:  Glucocorticoid-induced pancreatitis in children . Pediatrics 41:428-437, 1968;.
10 +
Ingle DJ:  The production of glycosuria in the normal rat by means of 17-hydroxy-11-dehydrocorticosterone . Endocrinology 29:649-652, 1941;.
11 +
Ingle DJ, et al:  A comparison of adrenal steroid diabetes and pancreatic diabetes in the rat . Endocrinology 37:341-356, 1945;.
12 +
Bookman JJ, et al:  Steroid diabetes in man: The development of diabetes during treatment with cortisone and corticotropin . Diabetes 2:100-110, 1953;.
13 +
Sprague RG:  Diabetes mellitus associated with chronic relapsing pancreatitis . Proc Staff Meet Mayo Clin 22:553-558, 1947;.
14 +
Keller P, et al:  Plasma-insulin levels in "pancreatic diabetes." Lancet 2:1211-1213, 1965;.
15 +
Rodriguez J:  Acute pancreatitis with fat necrosis, complicated by diabetic coma . JAMA 82:203-204, 1924;.
16 +
Steiner MM, Tracy PC:  Diabetic coma, acute pancreatitis and Bacillus welchii peritonitis . Am J Dis Child 65:36-45, 1943;.
17 +
Tully GT, Lowenthal JJ:  The diabetic coma of acute pancreatitis . Ann Intern Med 48:310-319, 1958;.
18 +
Hughes PD:  Diabetic acidosis with acute pancreatitis . Br J Surg 49:90-91, 1961;.
19 +
Ingle DJ:  Experimental steroid diabetes . Diabetes 5:187-192, 1956;.
20 +
McCullagh EP:  Diabetogenic action of the pituitary: Clinical observations . Diabetes 5:223-232, 1956;.
21 +
Polachek AA:  Steroid diabetes . Maryland Med J 4:195-199, 1955;.
22 +
Thorn GW, Ranold AE, Cahill GF Jr:  The adrenal and diabetes: Some interactions and interrelations . Diabetes 8:337-351, 1959;.
23 +
Berg E-G:  Über Schäden und Nebenwirkungen bei der therapeutischen Verwendung von Cortison und ähnlichen Steroidhormonen . Munchen Med Wschr 98:1614, 1956;.
24 +
Ranney HM, Gellhorn A:  The effect of massive prednisone and prednisolone therapy on acute leukemia and malignant lymphomas . Am J Med 22:405-413, 1957;.
25 +
Blereau RP, Weingarten CM:  Diabetic acidosis secondary to steroid therapy . New Engl J Med 271:836, 1964;.
26 +
Miller SEP, Neilson JM:  Clinical features of the diabetic syndrome appearing after steroid therapy . Postgrad Med J 40:660-669, 1964;.
27 +
Alavi IA, Sharma BK, Pillay VKG:  Steroid-induced diabetic ketoacidosis . Am J Med Sci 262:15-23, 1971;.
28 +
Boyer MH:  Hyperosmolar anacidotic coma in association with glucocorticoid therapy . JAMA 202:1007-1009, 1967;.
29 +
Pierce LE, O'Brien JJ:  Hyperglycemic coma associated with corticosteroid therapy . New York J Med 69:1785-1787, 1969;.
30 +
Spenney JG, Eure CA, Kreisberg RA:  Hyperglycemic, hyperosmolar, nonketoacidotic diabetes: A complication of steroid and immunosuppressive therapy . Diabetes 18:107-110, 1969;.
31 +
Limas CJ, Samad A, Seff D:  Hyperglycemic nonketotic coma as complication of steroid therapy . New York J Med 71:1542-1543, 1971;.
32 +
Katz LA, Spiro HM:  Gastrointestinal manifestations of diabetes . New Engl J Med 275:1350-1361, 1966;.
33 +
Bridgwater AB, et al:  Transient increase in blood sugar following experimental pancreatitis . Am J Physiol 200:851-854, 1961;.
34 +
Bossak ET, Joelson RH:  Acute pancreatitis complicating diabetes mellitus . Arch Intern Med 97:201-207, 1956;.
35 +
Blumenthal HT, Probstein JG, Berns AW:  Interrelationship of diabetes mellitus and pancreatitis . Arch Surg 87:844-850, 1963;.
36 +
Tilney NL, Collins JJ Jr, Wilson RE:  Hemorrhagic pancreatitis: A fatal complication of renal transplantation . New Engl J Med 274:1051-1057, 1966;.
37 +
Heuser E, et al:  Subcutaneous fat necrosis with acute hemorrhagic pancreatitis: A case in a child with steroid-resistant nephrosis treated with 6mercaptopurine . Calif Med 106:58-63, 1967;.
38 +
Apostolou K, et al:  Immunity to the lethal effects of acute pancreatitis . Surg Forum 16:382-384, 1965;.

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Lazarus SS, Bencosme SA:  Alterations of pancreas during cortisone diabetes in rabbits . Proc Soc Exp Biol Med 89:114-118, 1955;.
2 +
Stumpf HH, Wilens SL, Somoza C:  Pancreatic lesions and peripancreatic fat necrosis in cortisonetreated rabbits . Lab Invest 5:224-235, 1956;.
3 +
Carone FA, Liebow AA:  Acute pancreatic lesions in patients treated with Acth and adrenal corticoids . New Engl J Med 257:690-697, 1957;.
4 +
Baar HS, Wolff OH:  Pancreatic necrosis in cortisone-treated children . Lancet 1:812-815, 1957;.
5 +
Marczynska-Robowska M:  Pancreatic necrosis in a case of Still's disease . Lancet 1:815-816, 1957;.
6 +
Bourne MS, Dawson H:  Acute pancreatitis complicating prednisolone therapy . Lancet 2:1209-1210, 1958;.
7 +
Oppenheimer EH, Boitnott JK:  Pancreatitis in children following adrenal cortico-steroid therapy . Bull Hopkins Hosp 107:297-306, 1960;.
8 +
Nelp WB:  Acute pancreatitis associated with steroid therapy . Arch Intern Med 108:102-110, 1961;.
9 +
Riemenschneider TA, Wilson JF, Vernier RL:  Glucocorticoid-induced pancreatitis in children . Pediatrics 41:428-437, 1968;.
10 +
Ingle DJ:  The production of glycosuria in the normal rat by means of 17-hydroxy-11-dehydrocorticosterone . Endocrinology 29:649-652, 1941;.
11 +
Ingle DJ, et al:  A comparison of adrenal steroid diabetes and pancreatic diabetes in the rat . Endocrinology 37:341-356, 1945;.
12 +
Bookman JJ, et al:  Steroid diabetes in man: The development of diabetes during treatment with cortisone and corticotropin . Diabetes 2:100-110, 1953;.
13 +
Sprague RG:  Diabetes mellitus associated with chronic relapsing pancreatitis . Proc Staff Meet Mayo Clin 22:553-558, 1947;.
14 +
Keller P, et al:  Plasma-insulin levels in "pancreatic diabetes." Lancet 2:1211-1213, 1965;.
15 +
Rodriguez J:  Acute pancreatitis with fat necrosis, complicated by diabetic coma . JAMA 82:203-204, 1924;.
16 +
Steiner MM, Tracy PC:  Diabetic coma, acute pancreatitis and Bacillus welchii peritonitis . Am J Dis Child 65:36-45, 1943;.
17 +
Tully GT, Lowenthal JJ:  The diabetic coma of acute pancreatitis . Ann Intern Med 48:310-319, 1958;.
18 +
Hughes PD:  Diabetic acidosis with acute pancreatitis . Br J Surg 49:90-91, 1961;.
19 +
Ingle DJ:  Experimental steroid diabetes . Diabetes 5:187-192, 1956;.
20 +
McCullagh EP:  Diabetogenic action of the pituitary: Clinical observations . Diabetes 5:223-232, 1956;.
21 +
Polachek AA:  Steroid diabetes . Maryland Med J 4:195-199, 1955;.
22 +
Thorn GW, Ranold AE, Cahill GF Jr:  The adrenal and diabetes: Some interactions and interrelations . Diabetes 8:337-351, 1959;.
23 +
Berg E-G:  Über Schäden und Nebenwirkungen bei der therapeutischen Verwendung von Cortison und ähnlichen Steroidhormonen . Munchen Med Wschr 98:1614, 1956;.
24 +
Ranney HM, Gellhorn A:  The effect of massive prednisone and prednisolone therapy on acute leukemia and malignant lymphomas . Am J Med 22:405-413, 1957;.
25 +
Blereau RP, Weingarten CM:  Diabetic acidosis secondary to steroid therapy . New Engl J Med 271:836, 1964;.
26 +
Miller SEP, Neilson JM:  Clinical features of the diabetic syndrome appearing after steroid therapy . Postgrad Med J 40:660-669, 1964;.
27 +
Alavi IA, Sharma BK, Pillay VKG:  Steroid-induced diabetic ketoacidosis . Am J Med Sci 262:15-23, 1971;.
28 +
Boyer MH:  Hyperosmolar anacidotic coma in association with glucocorticoid therapy . JAMA 202:1007-1009, 1967;.
29 +
Pierce LE, O'Brien JJ:  Hyperglycemic coma associated with corticosteroid therapy . New York J Med 69:1785-1787, 1969;.
30 +
Spenney JG, Eure CA, Kreisberg RA:  Hyperglycemic, hyperosmolar, nonketoacidotic diabetes: A complication of steroid and immunosuppressive therapy . Diabetes 18:107-110, 1969;.
31 +
Limas CJ, Samad A, Seff D:  Hyperglycemic nonketotic coma as complication of steroid therapy . New York J Med 71:1542-1543, 1971;.
32 +
Katz LA, Spiro HM:  Gastrointestinal manifestations of diabetes . New Engl J Med 275:1350-1361, 1966;.
33 +
Bridgwater AB, et al:  Transient increase in blood sugar following experimental pancreatitis . Am J Physiol 200:851-854, 1961;.
34 +
Bossak ET, Joelson RH:  Acute pancreatitis complicating diabetes mellitus . Arch Intern Med 97:201-207, 1956;.
35 +
Blumenthal HT, Probstein JG, Berns AW:  Interrelationship of diabetes mellitus and pancreatitis . Arch Surg 87:844-850, 1963;.
36 +
Tilney NL, Collins JJ Jr, Wilson RE:  Hemorrhagic pancreatitis: A fatal complication of renal transplantation . New Engl J Med 274:1051-1057, 1966;.
37 +
Heuser E, et al:  Subcutaneous fat necrosis with acute hemorrhagic pancreatitis: A case in a child with steroid-resistant nephrosis treated with 6mercaptopurine . Calif Med 106:58-63, 1967;.
38 +
Apostolou K, et al:  Immunity to the lethal effects of acute pancreatitis . Surg Forum 16:382-384, 1965;.

Correspondence

Submit a Letter
CME
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Clear Answers | Save For Later
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Compression-Only CPR: Pushing the Science Forward
Cone
AAM 2010;304:1493-1495.
All you need to read in the other general journals
BMJ 2010;341:c5893-c1494.
Submit a Comment

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

© 2013 American Medical Association. All Rights Reserved.
Powered bySilverchair Information Systems