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March 1973, Vol 125, No. 3 >
Article | March 1973

Benignity of Neonatal Tumors FREE

W. S. Lowry, MD; Barbara E. Lowry, MD
Am J Dis Child. 1973;125(3):460. doi:10.1001/archpedi.1973.04160030110027.
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To the Editor.  —We would like to add a postscript to the discussion on the benign nature of neonatal cancer.1 It may be that acute lymphoblastic leukemia can be added to the list of diseases mentioned. This disease is distinctly uncommon in infants under 1 year, accounting for less than 10% of all cases. The incidence then rises steeply to a peak at 3 years. This pattern is not seen in the rare childhood cases of acute myeloblastic leukemia where there is no particular age distribution.Court Brown and Doll2 postulated that the peak was due to a latent period required for some unknown etiologic agent to exert its full effect. It may be, however, that passive immunologic factors keep the disease at bay in early life.Supporting evidence for this concept grows: in Burkitt lymphoma the period of protection extends for a longer time than in other

REFERENCES

1 +
Lowry WS, Bolande RP:  Benignity of neonatal tumors . Am J Dis Child 123:85-86, 1972;.
2 +
Court Brown WM, Doll R:  Leukemia in childhood . Br Med J 1:981-988, 1961;.
3 +
Pierce ML, et al:  Epidemiology and survival in leukemia . Cancer 23:1296-1302, 1969;.
4 +
Seidman H:  Cancer of the breast . Cancer 24:1355-1378, 1969;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Lowry WS, Bolande RP:  Benignity of neonatal tumors . Am J Dis Child 123:85-86, 1972;.
2 +
Court Brown WM, Doll R:  Leukemia in childhood . Br Med J 1:981-988, 1961;.
3 +
Pierce ML, et al:  Epidemiology and survival in leukemia . Cancer 23:1296-1302, 1969;.
4 +
Seidman H:  Cancer of the breast . Cancer 24:1355-1378, 1969;.

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